Results 171 to 180 of about 69,772 (247)

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

PhyCysID: Plant Cystatin Protein Prediction by an Artificial Intelligence Approach. [PDF]

J Chem Inf Model
Aqil S, Cadavid IC, Rodrigues NF, Balbinott N, Zanatta G, Margis R.   +5 more
europepmc   +1 more source

Cathepsin B - indicator for the release of lysosomal cyasteine proteinases in severe trauma and inflammation [PDF]

, 1990
Assfalg-Machleidt, Irmgard, Billing, Arend, Jochum, Marianne, Joka, Theo, Machleidt, Werner, Nast-Kolb, Dieter, Rothe, Gregor, Scheuber, Heinz- Peter, Siebeck, Matthias, Valet, Günter, Zauner, Rita   +10 more
core   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Neutrophil dynamics in pulmonary fibrosis: pathophysiological and therapeutic perspectives. [PDF]

Eur Respir Rev
Crowley LE, Stockley RA, Thickett DR, Dosanjh D, Scott A, Parekh D.   +5 more
europepmc   +1 more source

Increased levels of two distinct elastase-like hydrolases in plasma during septicemia [PDF]

, 1983
Duswald, Karl-Heimo, Goldberg, David M., Jochum, Marianne, Nelles, L. P., Schnebli, H. P.   +4 more
core   +1 more source

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

Matrix Metalloproteinase Inhibition in Melanoma. [PDF]

Exp Dermatol
Zhang E, Thakur V, Bedogni B.
europepmc   +1 more source

VIVID: A qPCR‐Based Platform for Sensitive and Quantitative In Vivo Tracking of Extracellular Vesicles

Advanced Functional Materials, EarlyView.
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian, Talin Ebrahimian, Jonathan Miranda O'Connor, Janusz Rak, Stephanie Lehoux, Maryam Tabrizian   +5 more
wiley   +1 more source

The Multifaceted Roles of Neutrophil Death in COPD and Lung Cancer. [PDF]

J Respir Biol Transl Med
Wan A, Chen D.
europepmc   +1 more source