Results 281 to 290 of about 10,300,849 (340)

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Dynamic Changes in Antibodies and Proteome in Breast Milk of Mothers Infected with Wild-Type SARS-CoV-2 and Omicron: A Longitudinal Study. [PDF]

Nutrients
Guo Y, Li C, Tan M, Chen Y, Zhu S, Zhi C, Zhu J.   +6 more
europepmc   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Iron-sensing and redox properties of the hemerythrin-like domains of Arabidopsis BRUTUS and BRUTUS-LIKE2 proteins. [PDF]

Nat Commun
Pullin J, Rodríguez-Celma J, Franceschetti M, Mundy JEA, Svistunenko DA, Bradley JM, Le Brun NE, Balk J.   +7 more
europepmc   +1 more source

Proteomics approach identifies aqueous humor biomarkers in retinal diseases. [PDF]

Commun Med (Lond)
Huang K, Schofield C, Nguy T, Dere R, Wolowski V, Siebourg-Polster J, Dieckmann A, Garweg JG, Chang M, Honigberg L, Hackney J, Indjeian VB.   +11 more
europepmc   +1 more source

Site-2 protease Sll0528 interacts with RbcR to regulate carbon/nitrogen homeostasis in the cyanobacterium <i>Synechocystis</i> sp. PCC 6803. [PDF]

Front Microbiol
Lin S, Zheng T, Mo Y, Zhang G, Chen G.
europepmc   +1 more source

Long-term GABA supplementation mitigates anxiety by modulating complement and neuroinflammatory pathways. [PDF]

NPJ Sci Food
Xu J, Ge Z, Wang H, Zhang C, Xu J, Li Y, Yang X, Zhang L, Li Z, Liu Z, Wang G, Du J.   +11 more
europepmc   +1 more source

Effect of Ultrasound Time on Structural and Gelling Properties of Pea, Lupin, and Rice Proteins. [PDF]

Gels
Riquelme N, Díaz-Calderón P, Luarte A, Arancibia C.   +3 more
europepmc   +1 more source

Effect of Proteins on the Network Formation and Degradation of Peroxide Cross-Linked Natural Rubber Elucidated by Time-Domain NMR. [PDF]

Polymers (Basel)
Nimpaiboon A, González-Jiménez A, Pérez-Aparicio R, Martín-Salamanca F, Zepeda-Rodríguez Z, López-Valentín J, Sakdapipanich J.   +6 more
europepmc   +1 more source

Temporal proteome profiling of Botrytis cinerea reveals proteins involved in plant invasion and survival. [PDF]

Sci Rep
Singh S, Hegde M, Kaur I, Adlakha N.
europepmc   +1 more source