Results 21 to 30 of about 6,344,955 (306)
Electron Transfer in Proteins [PDF]
Electron-transfer (ET) reactions are key steps in a diverse array of biological transformations ranging from photosynthesis to aerobic respiration. A powerful theoretical formalism has been developed that describes ET rates in terms of two parameters ...
Gray, Harry B., Winkler, Jay R.
core +1 more source
Protein-protein interaction prediction for targeted protein degradation [PDF]
AbstractProtein-protein interactions (PPIs) play a fundamental role in various biological functions; thus, detecting PPI sites is essential for understanding diseases and developing new drugs. PPI prediction is of particular relevance for the development of drugs employing targeted protein degradation, as their efficacy relies on the formation of a ...
Oliver Orasch +5 more
openaire +2 more sources
Influences of Excluded Volume of Molecules on Signaling Processes on Biomembrane [PDF]
We investigate the influences of the excluded volume of molecules on biochemical reaction processes on 2-dimensional surfaces using a model of signal transduction processes on biomembranes.
A Ashkenazi +56 more
core +8 more sources
Untying Knots in Proteins [PDF]
A shoelace can be readily untied by pulling its ends rather than its loops. Attempting to untie a native knot in a protein can also succeed or fail depending on where one pulls.
Cieplak, Marek +3 more
core +2 more sources
We are proud to present the first edition of the Protein–protein interactions Section of Current Opinion in Structural Biology. The Section is new, but the topic has been present in the journal from the very start. Volume 1, Issue 1, dated February 1991, had a review by Janin entitled Protein–protein interactions and assembly, and others by Bode and ...
Janin, Joel, Bonvin, Alexandre M. J. J.
openaire +3 more sources
Transient protein-protein interactions [PDF]
Transient complexes are crucial for diverse biological processes such as biochemical pathways and signaling cascades in the cell. Here, we give an overview of the transient interactions; the importance of transient interactions as drug targets; and the structural characterization of transient protein-protein complexes based on the geometrical and ...
Saliha Ece, Acuner Ozbabacan +3 more
openaire +2 more sources
Competitive adsorption of plasma proteins at solid—liquid interfaces [PDF]
The competitive adsorption of human serum albumin (HSA), human immuno-γ-globulin (HIgG) and human fibrinogen (HFb) onto polystyrene (PS) at 20° C and a pH of 7.35 (phosphate-buffered saline) was studied.
Breemhaar, W. +3 more
core +3 more sources
Factor VIII C-domains are believed to have specific functions in cofactor activity and in interactions with von Willebrand factor. We have previously shown that factor VIII is co-targeted with von Willebrand factor to the Weibel-Palade bodies in blood ...
Eduard H.T.M. Ebberink +7 more
doaj +1 more source
Urine Parameters in Patients with COVID-19 Infection
A urine test permits the measure of several urinary markers. This is a non-invasive method for early monitoring of potential kidney damage. In COVID-19 patients, alterations of urinary markers were observed.
Maria Morello +6 more
doaj +1 more source
Detergents and Chaotropes for Protein Solubilization before Two-Dimensional Electrophoresis [PDF]
Because of the outstanding separating capabilities of two-dimensional electrophoresis for complete proteins, it would be advantageous to be able to apply it to all types of proteins.
Chevallet, Mireille +3 more
core +4 more sources

