Results 321 to 330 of about 13,339,631 (403)

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Nuclear Fraction Proteome Analyses During rAAV Production of AAV2-Plasmid-Transfected HEK-293 Cells. [PDF]

Int J Mol Sci
Golm SK, Hoffrogge R, Müller KM.
europepmc   +1 more source

CRISPR-mediated proximity labeling unveils ABHD14B as a host factor to regulate HBV cccDNA transcriptional activity. [PDF]

Hepatol Commun
Sekiba K, Miyake N, Miyakawa Y, Shibata C, Seimiya T, Kishikawa T, Fujishiro M, Otsuka M.   +7 more
europepmc   +1 more source

Prediction of pathogenic mutations in human transmembrane proteins and their associated diseases via utilizing pre-trained Bio-LLMs. [PDF]

Commun Biol
Cao L, Quan L, Chen Q, Zhang B, Zhang Z, Peng L, Wang J, Jiang Y, Nie L, Li G, Wu T, Lyu Q.   +11 more
europepmc   +1 more source

An Overview of Advancements in Proteomic Approaches to Enhance Livestock Production and Aquaculture. [PDF]

Animals (Basel)
Jitjumnong J, Taweechaipaisankul A, Lin JC, Wongchanla S, Chuwatthanakhajorn S, Lin CJ, Khang LTP, Linh NV, Sangsawad P, Dinh-Hung N, Tang PC, Moonmanee T.   +11 more
europepmc   +1 more source

Mesenchymal Stem Cell-Derived Extracellular Vesicles: Emerging Therapies for Neurodegenerative Diseases. [PDF]

Int J Nanomedicine
Chen P, Wang F, Ling B, Zhu Y, Lin H, Huang J, Wang X.   +6 more
europepmc   +1 more source

Identification of plasma proteins associated with seizures in epilepsy: A consensus machine learning approach. [PDF]

PLoS One
Ashtiani SH, Akel S, Banote RK, Asztely F, Zelano J.   +4 more
europepmc   +1 more source

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Intrinsically unstructured proteins and their functions

Nature Reviews Molecular Cell Biology, 2005
H Jane Dyson, Peter E Wright, Patrick S Sullivan   +2 more
exaly   +2 more sources

Protein–protein interactions

Biochemical Society Transactions, 2010
In the present article, we describe the two standard high-throughput methods for identification of protein complexes: two-hybrid screens and TAP (tandem affinity purification) tagging. These methods have been used to characterize the interactome of Saccharomyces cerevisiae, showing that the majority of proteins are part of complexes, and that complexes
Williamson, Mike P., Sutcliffe, Michael J.   +1 more
openaire   +4 more sources