Results 161 to 170 of about 186,195 (263)

Clinicopathological Analysis of Patients with Isolated Hematuria and/or Mild Proteinuria. [PDF]

Int J Gen Med
Tang J, Luo P, He M, Ning L, Tan Z.
europepmc   +1 more source

Risk factors associated with progression from pre‐eclampsia to eclampsia: A prospective cohort study and population‐wide data analysis

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Younger maternal age and lower socioeconomic status emerged as key risk factors for progression from pre‐eclampsia to eclampsia in two low‐ and middle‐income countries (Uganda and Ecuador), challenging the traditional focus on disease severity alone. This suggests a need to broaden risk assessment criteria.
Annettee Nakimuli, Brittany A. Jasper, Sarah Nakubulwa, Moses Adroma, Jackline Akello, Imelda Namagembe, Musa Sekikubo, Eve Nakabembe, Ashley Moffett, Catherine E. Aiken   +9 more
wiley   +1 more source

Coenzyme Q10 supplementation in adult-onset focal segmental glomerulosclerosis caused by the Chinese common pathogenic variant c.737G > A (p.Ser246Asn) in the <i>COQ8B</i> gene. [PDF]

Ren Fail
Jin S, Shi Y, Lin P, Liu H, Xu X, Dai X, Jiang G, Ding X, Lin F.   +8 more
europepmc   +1 more source

Risk factors for immediate postpartum sickle cell disease‐specific maternal morbidity

British Journal of Haematology, EarlyView.
A hypothetical model describing the associations found in the analysis of factors contributing to the postpartum composite outcome. Risk factors in yellow boxes were significant only in univariate analysis; risk factors in green boxes were significant in multivariable analysis. Created with biorender.com.
Joanna Loh, Kevin H. M. Kuo, Ilinca Georgescu, Stella Wang, Ella Huszti, Nadine Shehata, A. Kinga Malinowski   +6 more
wiley   +1 more source

Time-Weighted Average Proteinuria and Renal Function Decline in IgA Nephropathy: A Retrospective Cohort Study. [PDF]

Int J Nephrol Renovasc Dis
Xu R, Cao T, Liao Y, Chen Y, Yu Y, Guo J, Zhong A, Chen X, Xu Y, Wan Q.   +9 more
europepmc   +1 more source

GNS561 (ezurpimtrostat), a small basic lipophilic molecule, prevents lupus phenotype in a pristane‐induced lupus mouse model

British Journal of Pharmacology, EarlyView.
Background and Purpose Systemic lupus erythematosus is an autoimmune, multisystemic disease affecting all organs in the body. Accrued evidence has elucidated a role for autophagy in the onset and severity of systemic lupus erythematosus. The antimalarial drug hydroxychloroquine constitutes the cornerstone of standard of care for systemic lupus ...
Eya Toumi, Eloïne Bestion, Muriel Militello, Hubert Lepidi, Anne Plauzolles, Nathalie Bardin, Daniel Bertin, Laurent Chiche, Jean‐Louis Mege, Philippe Halfon, Soraya Mezouar   +10 more
wiley   +1 more source

Predictive role of cystatin C and increased proteinuria in early assessment of acute renal toxicity in patient poisoned by nephrotoxic drugs and poisons. [PDF]

BMC Pharmacol Toxicol
Ali EMA, Yousef EAM, Helal MAE, Mohammed MH, Zaghary MMS, Elnabi MAH.   +5 more
europepmc   +1 more source

Advancing antihypertensive drug development

British Journal of Pharmacology, EarlyView.
Hypertension affects more than a billion individuals worldwide and remains a major cause of cardiovascular morbidity and mortality. Despite advances in therapies, optimal blood pressure control remains elusive for many patients because of treatment resistance, adverse effects, and adherence challenges.
Fay Pu, Yanrong Liu, Fozia Zahir Ahmed, Xin Wang, Darren Green, Hongyuan Zhang   +5 more
wiley   +1 more source

SGLT2 Inhibitors in Glomerulonephritis: Beyond Nephroprotection? [PDF]

J Clin Med
Del Vecchio L, Peiti S, Pucci Bella G, Locatelli F.   +3 more
europepmc   +1 more source

Artemisinins in autoimmune diseases: effects and mechanisms in systemic lupus erythematosus and rheumatoid arthritis

British Journal of Pharmacology, EarlyView.
Abstract Autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) result from immune self‐tolerance loss, causing tissue damage. Standard treatments targeting late‐stage inflammation often have serious side effects. Artemisinin, known for its antimalarial properties, shows potential immunomodulatory effects.
Fanchao Zhou, Guoming Li, Ruixiang Tan, Guodong Wu, Changsheng Deng   +4 more
wiley   +1 more source