Results 81 to 90 of about 150,037 (306)
Arthritis &Rheumatology, EarlyView.Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó +84 more
wiley +1 more source
PROTEINÚRIA: AVALIAÇÃO CLÍNICA E LABORATORIAL
Clinical and Biomedical Research, 2020 Neste artigo, apresentamos uma revisão geral dos aspectos clínicos e laboratoriais do paciente com proteinúria. A proteinúria reflete um aumento na permeabilidade do capilar glomerular.
José Vanildo Morales +2 more
doaj
Haseki Tıp Bülteni, 2019 Aim:To determine the risk factors for preeclampsia in isolated gestational proteinuria and to compare perinatal outcomes between women who did and did not develop preeclampsia.Methods:Seventy-six pregnants, who were diagnosed with isolated proteinuria ...
Betül Dündar +2 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective To assess the 2022 American College of Rheumatology (ACR)/EULAR classification criteria for antineutrophil cytoplasmic antibody–associated vasculitis (AAV) in children with chronic small‐to‐medium vessel vasculitis. Methods A cohort of 574 patients, identified by physician's diagnosis (MD‐diagnosis) in A Registry of Childhood Vasculitis, was ...
David A. Cabral +41 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi +9 more
wiley +1 more source
Characteristics of Proteinuria in Endemic Nephropathy [PDF]
, 1982 Summary: Subjects living in the endemic area of Posavina round Slavonski Brod have a significantly greater incidence of proteinuria (13.6%) than those living under the same conditions in the area where endemic nephropathy has not been observed (5.5 ...
Aleraj, B. +7 more
core +1 more source
IgG Glycosylation‐Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis
Arthritis &Rheumatology, EarlyView.Objective Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end‐stage kidney disease and increased mortality. IgG from patients with LN displays abnormal glycosylation, contributing to podocyte injury.
Rohit Upadhyay +3 more
wiley +1 more source
Massive Urinary Protein Excretion Associated with Greater Neonatal Risk in Preeclampsia
American Journal of Perinatology Reports, 2017 Objective The objective of this study was to compare clinical outcomes of preeclamptic pregnancies according to the proteinuria level. Study Design Secondary analysis of a multicenter prospective cohort study of women with preeclampsia (PE ...
Julio Mateus +10 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf +15 more
wiley +1 more source
Lower levels of proteinuria are associated with elevated mortality in incident dialysis patients.
PLoS ONE, 2019 IntroductionProteinuria is a potent predictor of adverse events in general, although a few large studies have reported a J-shaped association between proteinuria and mortality in individuals with glomerular filtration rate
Manabu Hishida +5 more
doaj +1 more source