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Antimicrobial Peptides from Marine Proteobacteria [PDF]
Marine Drugs, 2013 After years of inadequate use and the emergence of multidrug resistant (MDR) strains, the efficiency of “classical” antibiotics has decreased significantly. New drugs to fight MDR strains are urgently needed. Bacteria hold much promise as a source of unusual bioactive metabolites.
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Genome reduction in the α-Proteobacteria
Current Opinion in Microbiology, 2005More than 20 alpha-proteobacterial genomes are currently available. These range in size from 1-9 Mb and represent excellent model systems for evolutionary studies of the organizational features of bacterial genomes. Computational inferences have shown that genome reductions have occurred independently in lineages such as Rickettsia and Bartonella that ...
Björn, Sällström, Siv G E, Andersson
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Proteobacteria-like ferrochelatase in the malaria parasite
Current Genetics, 2003A gene encoding the heme biosynthetic enzyme ferrochelatase (FC) was found in the genomic DNA databases of Plasmodium spp. The predicted amino acid sequence of malarial FC is highly conserved and fairly well conserved by comparison with other orthologues. The FC genes of P. falciparum and P.
Shigeharu, Sato, R J M, Wilson
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Gene Arrangements and Phylogeny in the Class Proteobacteria
Journal of Theoretical Biology, 2001A simple method is presented for reconstructing phylogenetic trees on the basis of gene transposition. It is shown that differences in gene arrangements among genomes could allow us to determine whether a gene transposition event has occurred before or after species divergence from parsimonious considerations.
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