Results 231 to 240 of about 10,190 (249)
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2016
Identification of mutant proteins in biological samples is one of the emerging areas of proteogenomics. Despite the fact that only a limited number of studies have been published up to now, it has the potential to recognize novel disease biomarkers that have unique structure and desirably high specificity.
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Identification of mutant proteins in biological samples is one of the emerging areas of proteogenomics. Despite the fact that only a limited number of studies have been published up to now, it has the potential to recognize novel disease biomarkers that have unique structure and desirably high specificity.
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Proteogenomic Approach for Mycobacterium tuberculosis Investigation
2021Recent advances in MS/MS technology have made it possible to use proteomic data to predict protein-coding sequences. This approach is called proteogenomics, and it allows to correctly translate start and stop sites and to reveal new open reading frames.
Julia, Bespyatykh +2 more
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Proteogenomic Approach to UTR Peptide Identification
Journal of Proteome Research, 2019Recent sequencing technologies have highlighted translation of untranslated regions (UTRs) in genomes, although it remains unknown whether the translated products persist in a cell. Here, we propose a proteogenomic approach to UTR identification at the proteome level, which has been challenging due to the lack of corresponding sequences required for ...
Seunghyuk Choi +5 more
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Cancer proteogenomics: current impact and future prospects
Nature Reviews. Cancer, 2022D. Mani +8 more
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When proteogenomics helps ecotoxicology
2017As pioneers in biosurveillance, Kolkwitz and Marsson proposed, in 1909, a saprobic classification system for freshwater ecosystems based on the presence/absence of indicator species with differing organic pollution tolerances. Although chemical analysis is a useful tool to address this question, it is still impossible to quantify all chemical compounds
Almunia, C. +8 more
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Proteogenomics: Key Driver for Clinical Discovery and Personalized Medicine
2016Proteogenomics is a multi-omics research field that has the aim to efficiently integrate genomics, transcriptomics and proteomics. With this approach it is possible to identify new patient-specific proteoforms that may have implications in disease development, specifically in cancer.
Barbieri, Ruggero +5 more
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Proteogenomic Approaches for Diseasome Studies
During the last three decades, technological advancements in high-throughput next-generation sequencing have resulted in an increased understanding of proteomic and genomic data, aptly termed proteogenomics. Efforts in developing such approaches have not only been limited but also focused on protein identification and subcellular localization.Medhavi, Pokhriyall +3 more
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A proteogenomics data-driven knowledge base of human cancer.
Cell Systems, 2023Yuxing Liao +7 more
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Next Generation Sequencing Data and Proteogenomics
2016The field of proteogenomics has been driven by combined advances in next-generation sequencing (NGS) and proteomic methods. NGS technologies are now both rapid and affordable, making it feasible to include sequencing in the clinic and academic research setting. Alongside the improvements in sequencing technologies, methods in high throughput proteomics
Kelly V, Ruggles, David, Fenyö
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