Results 161 to 170 of about 13,155 (273)
A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer
The FEBS Journal, EarlyView.Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge +3 more
wiley +1 more source
The catalytic domain of protein kinase C chimeras modulates the affinity and targeting of phorbol ester-induced translocation [PDF]
, 2017 Blumberg, Peter M. +6 more
core +1 more source
ADAM17 and its proteolytic targets in disease pathogenesis
The FEBS Journal, EarlyView.ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
SIB1‐SEC23A undergo ER to chloroplast relocalization to mediate immunity in Arabidopsis thaliana
Journal of Integrative Plant Biology, EarlyView.SEC23A mediates membrane trafficking between the endoplasmic reticulum (ER) and Golgi apparatus and interacts with the immunity protein SIGMA FACTOR‐BINDING PROTEIN1 in Arabidopsis. Under stress, both proteins relocate from the ER to chloroplasts, suppressing photosynthesis genes and enhancing defense genes.
Jialin Peng +7 more
wiley +1 more source
Journal of Animal Physiology and Animal Nutrition, EarlyView.ABSTRACT Newly‐weaned piglets face challenges such as reduced feed intake, impaired gut function, and susceptibility to post‐weaning diarrhoea, increasing the need for dietary strategies that support gut health and growth. This study investigated the effects of dietary supplementation with butyric acid (BA), resistant potato starch (PS), and their ...
Kathryn Ruth Connolly +2 more
wiley +1 more source
LUCID: An Integrative Approach for Target Discovery and dsRNA Design in Plant Fungal Pathogens
Plant Biotechnology Journal, EarlyView.LUCID: A computational pipeline for RNAi‐based biofungicide design. ABSTRACT Phytopathogenic fungi pose an escalating threat to global food security and ecosystem stability, as resistance and environmental concerns diminish the effectiveness of conventional fungicides.
Lucía Jiménez‐Castro +4 more
wiley +1 more source
Development of metal-linked proteolysis targeting chimeras
, 2021 A via ubiquitina-proteossoma é um dos métodos celulares utilizados para a degradação de proteínas, onde ocorre a formação de uma cadeia de ubiquitina na proteína alvo, sinalizando-a para degradação no proteossoma. Para a formação da cadeia de ubiquitina é necessária a presença do enzima ativador de ubiquitina (E1), do enzima conjugador (E2) e do ...
openaire +1 more source
Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming
Plant Biotechnology Journal, EarlyView.Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska +2 more
wiley +1 more source
Three Decades of China's Bt Cotton: Achievements and Insights
Plant Biotechnology Journal, EarlyView.ABSTRACT Cotton is a vital natural fibre crop with significant economic value worldwide. In response to the threat of cotton bollworm (Helicoverpa armigera), the China government initiated a research project in 1992 to develop transgenic Bacillus thuringiensis (Bt) cotton.
Zhigang Meng +10 more
wiley +1 more source