Results 231 to 240 of about 599,323 (353)

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Exploring proteomic signatures in sepsis and non-infectious systemic inflammatory response syndrome. [PDF]

PLoS One
Ruiz-Sanmartín A, Ribas V, Suñol D, Chiscano-Camón L, Martín L, Bajaña I, Bastida J, Larrosa N, González JJ, Carrasco MD, Canela N, Ferrer R, Ruiz-Rodríguez JC.   +12 more
europepmc   +1 more source

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

Advanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil, Maria Anezaki, Alexandros Simistiras, Stavros Glentis, Nikolaos Scarmeas, Pantelis Hatzis, Konstantinos Rouskas, Antigone S. Dimas   +7 more
wiley   +1 more source

Early proteomic signatures of impaired maxillary bone remodeling under mechanical stress in type 1 diabetes mellitus. [PDF]

J Oral Biol Craniofac Res
Tobias-López LF, Trejo-Iriarte CG, García-Muñoz A, Gómez-Clavel JF.   +3 more
europepmc   +1 more source

Integrated Metabolomics and Proteomics Analysis to Provide Insights into Fish Muscle Atrophy by Dietary Clostridium Autoethanogenum Protein

Shihui Pan, Nan Bai, Zezhegn Qi, Chuwen Chen, Daisong Ma, Liang Zhenlin, Min Gu   +6 more
openalex   +1 more source

Halofuginone is a Molecular Glue Degrader of Integrin β4

Advanced Science, EarlyView.
Integrin β4 overexpression is linked to aggressive tumors and poor prognosis, but targeted therapies are lacking. We identified halofuginone (HF) as a molecular glue degrader that promotes integrin β4 degradation via the CRL4BWDR18 E3 ligase. HF suppresses tumor progression in vitro and in vivo, offering a new strategy for targeting oncogenic ...
Wei Gong, Di Yang, Junrui Tian, Yufei Chai, Tiantian Yu, Qingnan Wu, Yan Wang, Weimin Zhang, Qimin Zhan   +8 more
wiley   +1 more source

Proteomic profiling of bull spermatozoa and seminal plasma to inform the rational development of functionally targeted semen extenders for tropical cattle. [PDF]

Vet World
Sahiruddin S, Yusuf M, Diansyah AM, Masturi M, Herdis H, Maulana T, Sihombing VR, Rahmat R, Amrullah MF, Adam AAS, Said S, Alfian AM.   +11 more
europepmc   +1 more source

MassIVE MSV000100206 - Brevetoxicosis in Florida manatees (Trichechus manatus latirostris): Plasma proteomics for Florida red tide biomarkers

Rein, Kathleen S.
openalex   +1 more source

Rapid method towards proteomic analysis of dried blood spots by MALDI mass spectrometry

, 2019
Grace M. Samenuk, Andrea R. Kelley, George Perry, Stephan B. H. Bach   +3 more
openalex   +2 more sources

Proteomics Projects: Interaction Proteome: New tools for proteomics [PDF]

Journal of Proteome Research, 2006
openaire   +1 more source