Results 241 to 250 of about 591,485 (302)

Multi-omic analyses of the same sample using metabolomics, lipidomics, proteomics, phosphoproteomics, and glycoproteomics.

Chem Commun (Camb)
Wang Y, Peng X, Liu H, Gidley M, Kelly B, Pearce EL, Pearce EJ, Han X, Zhang H.   +8 more
europepmc   +1 more source

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI) in Alzheimer's disease: a scoping review of proteomic alterations in neurological tissues. [PDF]

Dement Neuropsychol
Vieira GH, Braga VHG, Mesquita IM, Rodrigues SS, Maia SD, Araújo GO, Sousa IMS, de Moura ALD.   +7 more
europepmc   +1 more source

LRRC4 Orchestrates AP2A1‐Containing Clathrin‐Coated Vesicles to Disrupt Mitochondrial Cristae and Restrict Glioblastoma Progression

Advanced Science, EarlyView.
LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li, Cheng Huang, Liangqi Jiang, Zhen Li, Qing Liu, Minghua Wu   +5 more
wiley   +1 more source

Biomarker investigation into human cerebrospinal fluid by proteomic approach.

, 2006
D'AGUANNO S, URBANI A, LUPISELLA S, CARELLI V, MELZI D'ERIL GV, BERNARDINI S, BARASSI A, FEDERICI G., PALLOTTI, FRANCESCO   +8 more
core  

Proteomic organ-specific signatures, ageing traits, disease risks and genetic architecture in an East Asian population. [PDF]

EBioMedicine
Bennett DA, Wang B, Xiao S, Wright N, Edris A, Wang Y, Millwood IY, Walters RG, Du H, Yang L, Chen Y, Avery D, Schmidt DV, Yu C, Sun D, Lv J, Hill M, Li L, Clarke R, Chen Z, China Kadoorie Biobank Collaborative Group.   +20 more
europepmc   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Proteomic profiling of pulpal and periapical diseases: a systematic review. [PDF]

Front Dent Med
Rai AS, Iype AM, Bhat R, Shetty P.
europepmc   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Multi‐Omics Profiling of High‐Grade Serous Ovarian Cancer Reveals an Inflammation‐Related Lipid Metabolism Subtype Associated With Platinum Resistance

Advanced Science, EarlyView.
Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao, Junyi Li, Bo Zheng, Wanshan Liu, Yaru Wang, Shufeng Wang, Ying Cui, Huiqin Guo, Hongxia Wang, Ting Xiao, Kun Qian, Jing Zuo   +11 more
wiley   +1 more source

Proteomic profile of the dentine pellicle modified with plant polyphenols and fluoride. [PDF]

Clin Oral Investig
Carvalho TS, Baumann T, Buzalaf MAR, Rios D, Hannig M, Niemeyer SH.   +5 more
europepmc   +1 more source