Results 261 to 270 of about 599,323 (353)

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

Proteomic analysis across Healthy-NAT-Tumor tissues uncovers clinically relevant biological events in esophageal squamous cell carcinoma. [PDF]

Brief Bioinform
Liu W, Wang W, Zheng DW, Ran YQ, Feng MX, Deng DX, Xu XE, Xu LY, Huang HH, Li EM.   +9 more
europepmc   +1 more source

Integration of Proteomic and Metabolomic Profiling as well as Metabolic Modeling for the Functional Analysis of Metabolic Networks

, 2010
Patrick May, Nils Christian, Oliver Ebenhöh, Wolfram Weckwerth, Dirk Walther   +4 more
openalex   +2 more sources

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

Comparative Morphological and Proteomic Characterization of Adipose Tissues from Different Anatomical Sites in Yili Horses. [PDF]

Biology (Basel)
Yang L, Song L, Lu Z, Yao X, Wang J, Zeng Y, Ren W, Luo P, Meng J.   +8 more
europepmc   +1 more source

Effect of dexamethasone on proteomics of endometrial fluid from mares susceptible to endometritis

, 2013
Tamarini Rodrigues Arlas, C.A. Wolf, Bianca Petrucci, J.F. Estanislau, Ricardo Macedo Gregory, Maria Inês Mascarenhas Jobim, Rodrigo Costa Mattos   +6 more
openalex   +2 more sources

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Integrative In Vivo and Proteomic Analysis of a <i>Bovistella utriformis</i> Polysaccharide Formulation Reveals Mechanisms of Enhanced Skin Wound Healing. [PDF]

Molecules
Maaloul A, Decara J, Valverde-Guillén P, Cárdenas-García C, Riquelme C, Pérez Manríquez C, López-Gambero AJ, Albendea Santana M, Marí-Beffa M, Araya-Rojas M, Fajardo V, Abdala-Díaz RT.   +11 more
europepmc   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source