Results 111 to 120 of about 147,662 (251)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Proteomics data collection : 4th ProDaC workshop: 15 August 2008, Amsterdam, The Netherlands

, 2009
ProDaC (Proteomics Data Collection), a "Coordination Action" within the 6th EU framework programme, was created to support the collection, distribution and public availability of data from proteomics experiments.
Levander, Fredrik, Michael Kohl, Helmut E. Meyer, Hardt, Tanja, Kohl, Michael, Levander, Fredrik,, Martin Eisenacher, Barsnes, Harald, Rolf Apweiler, Martens, Lennart, Kohl, M, Jari Häkkinen, Stephan, Christian, Harald Barsnes, Tanja Hardt, Häkkinen, Jari, Eisenacher, Martin, Christian Stephan, Häkkinen, Jari,, Hardt, Tania, Meyer, Helmut E, Lennart Martens, Apweiler, Rolf, Fredrik Levander, Lund University.   +24 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Correlating metabolites, lipids, and N-glycans in murine kidney microstructures via integrative mass spectrometry imaging

Nature Communications
Understanding how metabolites, lipids and glycans interact within tissues at the same cellular layer is key to uncovering their roles in health and disease. Herein, we present an integrative multi-omic mass spectrometry imaging (MSI) approach correlating
Nina Ogrinc, Rick Ursem, Hans Dalebout, Jesper Kers, Martin Giera, Manfred Wuhrer, Noortje de Haan   +6 more
doaj   +1 more source

Automated reporting from gel-based proteomics experiments using the open source Proteios database application

, 2007
The assembly of data from different parts of proteomics workflow is often a major bottleneck in proteomics. Furthermore, there is an increasing demand for the publication of details about protein identifications due to the problems with false-positive ...
Häkkinen, Jari, James, Peter,, Levander, Fredrik, James, Peter, Wårell, Kristofer, Gärdén, Per, Krogh, Morten, Levander, Fredrik,, Häkkinen, Jari,, Lund University., Wårell, Kristofer,   +10 more
core   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Plant Proteomics

, 2015
This special issue on "Plant Proteomics" aims to highlight the diverse applications of proteomics in understanding plant molecular responses to various biotic and abiotic challenges.

core  

Application of immobilized metal affinity chromatography in proteomics

, 2005
It has been proved that the progress of proteomics is mostly determined by the development of advanced and sensitive protein separation technologies.
Chiu, JF, He, QY, Sun, X
core   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Getting a grip on proteomics data - Proteomics Data Collection (ProDaC)

, 2009
In proteomics, rapid developments in instrumentation led to the acquisition of increasingly large data sets. Correspondingly, ProDaC was founded in 2006 as a Coordination Action project within the 6th European Union Framework Programme to support data ...
al, et, Häkkinen, Jari, Levander, Fredrik, Eisenacher, Martin, Aebersold, Ruedi, Kohl, Michael, Häkkinen, Jari,, Levander, Fredrik,, Hardt, Tania, Barsnes, Harald, Martens, Lennart, Lund University., Helsens, K   +12 more
core   +1 more source