Results 101 to 110 of about 147,662 (251)

Tumor-associated macrophages remodeling EMT and predicting survival in colorectal carcinoma

OncoImmunology, 2018
The immune contexture, a composition of the tumor microenvironment, plays multiple important roles in cancer stem cell (CSC) and epithelial–mesenchymal transition (EMT), and hence critically influences tumor initiation, progression and patient outcome ...
Si Li, Fangying Xu, Jing Zhang, Lili Wang, Yang Zheng, Xuesong Wu, Jing Wang, Qiong Huang, Maode Lai   +8 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

How do our cells build their protein interactome?

Nature Communications, 2018
Chaperones are cellular factors that help in the folding of newly synthesized polypeptides (or clients) and, in some cases, ensure their integration within larger complexes.
Benoit Coulombe, Philippe Cloutier, Marie-Soleil Gauthier   +2 more
doaj   +1 more source

Proteomics data collection : 2nd ProDaC workshop : 5 October 2007, Seoul, Korea

, 2008
Proteomics Data Collection (ProDaC) is an EU-funded "Coordination Action" within the 6th framework programme. It aims to simplify the publication, dissemination and utilization of proteomics data by establishing standards that will support broad data ...
Hardt, Tanja,, Stephan, Christian,, Häkkinen, Jari, Levander, Fredrik, Apweiler, Rolf,, Hamacher, Michael,, Eisenacher, Martin, Hardt, Tanja, Hamacher, Michael, Martens, Lennart,, Levander, Fredrik,, Häkkinen, Jari,, Meyer, Helmut E, Apweiler, Rolf, Mayer, Helmut E, Martens, Lennart, Mayer, Helmut E,, Lund University., Eisenacher, Martin,, Stephan, Christian   +19 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Plasma Proteome Database as a resource for proteomics research

PROTEOMICS, 2005
AbstractPlasma is one of the best studied compartments in the human body and serves as an ideal body fluid for the diagnosis of diseases. This report provides a detailed functional annotation of all the plasma proteins identified to date. In all, gene products encoded by 3778 distinct genes were annotated based on proteins previously published in the ...
Muthusamy, Babylakshmi, Hanumanthu, G., Suresh, Shubha, Rekha, B., Srinivas, D., Karthick, L., Vrushabendra, B. M., Sharma, Salil, Mishra, Goparani, Chatterjee, Pritam, Mangala, K. S., Nagaraj, Shivashankar H., Chandrika, K. N., Deshpande, Nandan, Suresh, M., Kannabiran, N., Niranjan, Vidya, Nalli, Anuradha, Prasad, T. S. Keshava, Arun, K. S., Reddy, Raghunath, Chandran, Sreenath, Jadhav, Trafina, Julie, D., Mahesh, M., John, S. Lynate, Palvankar, Kshitish, Sudhir, D., Bala, P., Rashmi, N. S., Vishnupriya, G., Dhar, Kaushik, Reshma, S., Chaerkady, Raghothama, Gandhi, T. K. B., Harsha, H. C., Mohan, S. Sujatha, Deshpande, Krishna S., Sarker, Malabika, Pandey, Akhilesh   +39 more
openaire   +5 more sources

Bridging proteomics and systems biology : What are the roads to be traveled?

, 2005
The comprehensive study of proteomes has become an important part of attempts to uncover the systemic properties of biological systems. Proteomics provides data of a quality which increasingly fulfills strict requirements of systems biology for ...
Souchelnytskyi, S,, Souchelnytskyi, Serhiy,   +1 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Paired proteomic analysis reveals protein alterations in sun-exposed skin of professional drivers

Scientific Reports
Professional drivers represent an ideal cohort for investigating the effects of solar radiation on skin due to their unique, asymmetric exposure to sun, a consequence of vehicle window orientations.
Amanda C. Camillo-Andrade, Lucas A. Sales, Juliana S. G. Fischer, Rosario Duran, Marlon D. M. Santos, Paulo C. Carvalho   +5 more
doaj   +1 more source

Discovery of circulating proteins associated to knee radiographic osteoarthritis

Scientific Reports, 2017
Currently there are no sufficiently sensitive biomarkers able to reflect changes in joint remodelling during osteoarthritis (OA). In this work, we took an affinity proteomic approach to profile serum samples for proteins that could serve as indicators ...
Lucía Lourido, Burcu Ayoglu, Juan Fernández-Tajes, Natividad Oreiro, Frauke Henjes, Cecilia Hellström, Jochen M. Schwenk, Cristina Ruiz-Romero, Peter Nilsson, Francisco J. Blanco   +9 more
doaj   +1 more source