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Residue and Intake Risk Assessment of Prothioconazole and Its Metabolite Prothioconazole-Desthio in Wheat Field

Environmental Monitoring and Assessment, 2017
In the environment, plants and animals in vivo, pesticides can be degraded or metabolized to form transformation products (TPs) or metabolites, which are even more toxic than parent pesticides. Hence, it was necessary to evaluate residue and risk of pesticides and their TPs (or metabolites). Here, a rapid, simple, and reliable method using QuEChERS and
Bizhang Dong, Jinghua Niu
exaly   +3 more sources

Toxicological effects of acute prothioconazole and prothioconazole-desthio administration on liver in male Chinese lizards (Eremias argus)

Chemosphere, 2022
Prothioconazole (PTC) is a high effective systemic fungicide, and one of its major metabolites is prothioconazole-desthio (PTC-d). Because of its wildly use in the farmland of China, the local eco-toxicological effects of PTC as well as PTC-d are needed to be concerned.
Yun, Xie   +4 more
openaire   +2 more sources

Dissipation of Prothioconazole and Its Metabolite Prothioconazole-Desthio in Rice Fields and Risk Assessment of Its Dietary Intake

Journal of Agricultural and Food Chemistry, 2019
Rice is an important food crop, with a long history of cultivation in China, and is one of the important staple foods for Chinese today. However, the occurrence of rice diseases has had a substantial impact on its yield. At present, chemical control is the main means of prevention and control of rice diseases.
Tong Zhou, JinSheng Duan, Mingna Sun
exaly   +3 more sources

Mechanism and Kinetics of Prothioconazole Photodegradation in Aqueous Solution

Journal of Agricultural and Food Chemistry, 2023
This study investigated the effects of light source, pH value, and NO3- concentration on the photodegradation of prothioconazole in aqueous solution. The half-life (t1/2) of prothioconazole was 173.29, 21.66, and 11.18 min under xenon, ultraviolet, and high-pressure mercury lamps, respectively. At pH values of 4.0, 7.0, and 9.0 under a xenon lamp light
Quan Gao   +5 more
openaire   +2 more sources

Enantiomeric separation of prothioconazole and prothioconazole‐desthio on chiral stationary phases

Chirality, 2019
AbstractProthioconazole is a type of broad‐spectrum triazole thione fungicide developed by the Bayer Company. Prothioconazole‐desthio is the main metabolite of prothioconazole in the environment. In our study, enantiomeric separation of prothioconazole and prothioconazole‐desthio was performed on various chiral stationary phases (CSPs) by high ...
Hui Liu, Wei Ding
openaire   +2 more sources

Effects of Exposure to Prothioconazole and Its Metabolite Prothioconazole-Desthio on Oxidative Stress and Metabolic Profiles of Liver and Kidney Tissues in Male Mice

Environmental Pollution, 2021
Prothioconazole (PTC), a popular agricultural fungicide, and its main metabolite prothioconazole-desthio (PTCd) are receiving great attention due to their toxicological effects in the non-target organisms. This study investigated their dosage-dependent (1 and 5 mg/kg BW/day) toxicological effects on oxidative stress and metabolic profiles of liver and ...
Wentao Zhu, Zhiqiang Zhou, Zhiyuan Meng
exaly   +3 more sources

Exposure to the fungicide prothioconazole and its metabolite prothioconazole-desthio induced hepatic metabolism disorder and oxidative stress in mice

Pesticide Biochemistry and Physiology, 2023
Prothioconazole (PTC), as a popular triazole fungicide, with its main metabolite prothioconazole desthio (PTC-d), have attracted widespread concern due to their widely use and toxicological effects on non-target organisms. However, toxic effects of study analyzed PTC and PTC-d on the hepatic metabolism of mammalian still remains unclear. In this study,
Lingyu, Hu   +4 more
openaire   +2 more sources

Comparison Between Prothioconazole and Prothioconazole-Desthio in Poison-Plate Mycelial Growth Assays of Fusarium graminearum

Plant Health Progress, 2022
The active ingredient prothioconazole is a demethylase inhibitor (DMI) widely used in numerous commercial fungicide formulations for crop protection. However, prothioconazole converts in planta to prothioconazole-desthio, which was found to be the primary active form inhibiting CYP51 activity in fungi.
Mikaela Breunig, Martin I. Chilvers
openaire   +1 more source

Enantioselective effect of chiral prothioconazole on the conformation of bovine serum albumin

International Journal of Biological Macromolecules, 2023
As a typical chiral triazole fungicide, the enantioselective toxicity of prothioconazole to environmental organisms is of increasing concern. Herein, the binding mechanism of chiral PTCs to BSA was investigated by multi-spectral technique and molecular docking.
Meiqing, Zhu   +7 more
openaire   +2 more sources

Toxification metabolism and treatment strategy of the chiral triazole fungicide prothioconazole in water

Journal of Hazardous Materials, 2022
Toxification metabolism of the chiral triazole fungicide prothioconazole in the environment has attracted an increasing amount of attention. To better understand the fate of prothioconazole in aquatic ecosystems and develop a treatment strategy, the stereoselective toxicity, degradation and bioconcentration of prothioconazole were investigated in water
Zhaoxian, Zhang   +5 more
openaire   +2 more sources

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