Results 191 to 200 of about 26,157 (280)
Electrochemical Regioselective Chalcogenocyclizations of 2‐Alkynylbenzamides in Flow
A sustainable electrochemical method enables regioselective 6‐endo‐dig chalcogeno‐cyclizations of ortho‐alkynylbenzamides in continuous flow. Using diphenyl diselenide as an electroactive coupling partner, the process avoids metals and stoichiometric oxidants, offering scalable access to selenium‐containing heterocycles.
Hanaa Gieman +2 more
wiley +1 more source
Organic azides are readily reduced to amines under mild conditions by ammonia borane complex, catalyzed by a low loading level of reusable Au nanoparticles supported on TiO2. We present the first protocol for the chemoselective reduction of organic azides to amines by ammonia borane complex. In the presence of a low catalytic amount of Au nanoparticles
Elisavet‐Maria Zantioti‐Chatzouda +5 more
wiley +1 more source
Streamlined Radiosynthesis of [18F]Fluproxadine (AF78): An Unprotected Guanidine Precursor Enables Efficient One-Step, Automation-Ready Labeling for Clinical Use. [PDF]
Chen X +9 more
europepmc +1 more source
Machine learning approach (ML) for rapid and accurate prediction of 1H‐NMR shifts in zinc complexes validated against experimental NMR data across multiple solvent environments. ABSTRACT Accurate prediction of NMR chemical shifts in transition metal complexes remains challenging due to the wide range of coordination environments and complex electronic ...
Jyothika R. Pillay +5 more
wiley +1 more source
Reversible Photoswitching of Donor-Acceptor Stenhouse Adducts in Water. [PDF]
Blandón-Cumbreras FG +6 more
europepmc +1 more source
Isolation and characterisation of endogenously labelled extracellular vesicles (EVs) from donor cells are timelapse imaged using intensity and lifetime microscopies to capture EV contact with filopodia and the plasma membrane (PM) of acceptor cells. Accumulation of EVs within and around filipodia could be observed and following passage through the PM ...
Eden Booth +3 more
wiley +1 more source
The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design
Thalidomide serves as a molecular nexus linking chemistry and biology: advances in synthesis and structural understanding enable protein degradation technologies, while its immunomodulatory activity underpins anti‐inflammatory and anticancer therapies.
Konstantina Nikovia +4 more
wiley +1 more source
Proline-Free Local Turn via N-Oxidation: Crystallographic and Solution Evidence for a Six-Membered N-O⋯H-N Ring. [PDF]
Zheng R +7 more
europepmc +1 more source

