Results 91 to 100 of about 35,987 (237)

Functional transition of Pak proto-oncogene during early evolution of metazoans

Oncogene, 2010
Akihiro Watari, N. Iwabe, H. Masuda, Masato Okada   +3 more
semanticscholar   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

The Molecular Basis of Cancer [PDF]

, 1998
After cardiovascular diseases, cancer is the second leading cause of death in America. Since 1990 over half a million Americans have died each year of some form of cance1; and the number and rate is still increasing.
Gorga, Frank
core   +1 more source

The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells

Oncogene, 2016
F. Blanco, M. Jimbo, J. Wulfkuhle, Isela R. Gallagher, Jianghong Deng, L. Enyenihi, Nicole C Meisner-Kober, Eric Londin, I. Rigoutsos, J. Sawicki, M. Risbud, A. Witkiewicz, P. Mccue, Wei Jiang, H. Rui, C. Yeo, E. Petricoin, J. Winter, J. Brody   +18 more
semanticscholar   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

The MYB proto-oncogene suppresses monocytic differentiation of acute myeloid leukemia cells via transcriptional activation of its target gene GFI1

Oncogene, 2014
Liang Zhao, Ping Ye, T. Gonda
semanticscholar   +1 more source

Liquid Crystalline Networks Hamper the Malignancy of Cancer Cells

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Liquid Crystalline Networks are used as scaffolds for the growth of A375 melanoma cells demonstrating to affect their malignancy. Indeed, only by contact, these materials reduces cell proliferation and colony formation capacity, while increasing the number of senescent cells and promoting the mesenchymal to epithelial transition.
Daniele Martella, Ignazia Tusa, Alessandro Tubita, Alessia Negri, Marco Turriani, Marta Rojas‐Rodríguez, Martina Salzano de Luna, Alessio Menconi, Camilla Parmeggiani, Elisabetta Rovida   +9 more
wiley   +1 more source

Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation [PDF]

, 2004
CULP, LA, EDSJO, A, KARLSSON, J, NILSSON, H, PAHLMAN, S, Pattyn, Filip, Speleman, Franki, Vandesompele, Jo   +7 more
core   +2 more sources

Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas

Oncogene, 2003
Charles T. Miller, Guoan Chen, Tarek G Gharib, Hong Wang, Dafydd G. Thomas, David E. Misek, T. Giordano, J. Yee, M. Orringer, S. Hanash, D. Beer   +10 more
semanticscholar   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source