Results 181 to 190 of about 8,187 (229)

The mas oncogene encodes an angiotensin receptor

, 1988
T. R. Jackson, M. R. Hanley, L. A. C. Blair, J. Marshall, M. Goedert   +4 more
core   +1 more source

Integrated analysis of ARHGAP6 potential function and prognostic value in acute myeloid leukemia. [PDF]

PLoS One
Yang D, Li Y, Ma P, Xiao F.
europepmc   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Virtual screening of novel alkaloids as potent inhibitors for G2032R-mutant ROS1 kinase in non-small-cell lung cancer. [PDF]

Sci Rep
Cho SC, Wang YW, Chu CA, Huang MC, Lee CT.   +4 more
europepmc   +1 more source

Single‐Cell Profiling Reveals Distinct Immune Hallmarks in Untreated Primary Colorectal and Liver Metastasis Cancers

Chronic Diseases and Translational Medicine, EarlyView.
Features the major cell type compositions among colon and liver metastasis. (A) The study design for single‐cell data analysis. (B) The annotated major cell types. Each type was labeled with a special color. (C) Dot plot of canonical marker genes for major cell types. (D) Bar plot of the percentage for each cell type in individuals. (E) Bar plot of the
Zhixun Zhao, Haipeng Chen, Xu Guan, Zheng Jiang, Zheng Liu, Ming Yang, Hengchang Liu, Tianli Chen, Shuangmei Zou, Yibo Gao, Xishan Wang   +10 more
wiley   +1 more source

Hsa_circ_0000437 promotes the progression of rheumatic valvular heart disease by activating the mitogen-activated protein kinase signaling pathways after sponging let-7f-5p and targeting RAS-like proto-oncogene B. [PDF]

Hum Cell
Zhu L, Li N, Shi H, Song J, Fang Z, Shen Q, Zhu X, Dan Y, Shao G, Sun L.   +9 more
europepmc   +1 more source

Characterization of the Interaction of Known G‐quadruplex Ligands With a Minimal i‐Motif Structure

Chemistry – A European Journal, EarlyView.
The destabilization of a minimal i‐Motif (iM) structure by TMPyP4 is driven by ligand recognition of one terminal iM structural domain. ABSTRACT Peculiar genomic regions are prone to evolve transiently from double‐helix DNA to noncanonical secondary structures in response to physiological stress.
Davide Auricchio, Marko Trajkovski, Janez Plavec, Claudia Sissi   +3 more
wiley   +1 more source

An <i>ETS2</i> Enhancer Variant May Modulate Gene Expression and Contribute to Defining a Genetic Risk Profile for SLE Susceptibility. [PDF]

Genes (Basel)
Latini A, De Benedittis G, Morgante C, Perricone C, Ceccarelli F, Conti F, Novelli G, Ciccacci C, Borgiani P.   +8 more
europepmc   +1 more source

Predicting cervical cancer DNA methylation from genetic data using multivariate CMMP

Canadian Journal of Statistics, EarlyView.
Abstract Epigenetic modifications link the environment to gene expression and play a crucial role in tumour development. DNA methylation, in particular, is gaining attention in cancer research, including cervical cancer, the focus of this study.
Hang Zhang, Steven Chen, Raymond Balise, Jiming Jiang, Nagi Ayad, J. Sunil Rao   +5 more
wiley   +1 more source

GSK-J4 Suppresses Tumorigenesis by Targeting the PERK-c-Myc Pathway Through Endoplasmic Reticulum Stress Activation in Tuberous Sclerosis Complex. [PDF]

Int J Mol Sci
Lei X, Lang T, Li P, Wu C.
europepmc   +1 more source