Results 151 to 160 of about 41,733 (183)

Melanocytic nevi excised during B-Raf proto-oncogene (BRAF) inhibitor therapy: A study of 19 lesions from 10 patients

Journal of the American Academy of Dermatology, 2015
Mai Hoang, Keith Flaherty, Adriano Piris   +2 more
exaly   +2 more sources

Programmed-cell-death-1-receptor-antagonists/proto-oncogene-protein-b-raf-inhibitors/mitogen-activated-protein-kinase-kinase-inhibitors

Reactions Weekly, 2018
openaire   +2 more sources

Efficacy of vemurafenib based regimens in colorectal cancer: A systematic review of clinical trials.

Journal of Clinical Oncology, 2023
e15566 Background: Colorectal cancer (CRC) is the 3rd most common cancer worldwide, and BRAF gene mutation is present in almost 10% of these cancers. It results in constitutive activation of the mitogen-activated protein kinase pathway (MAPKP).
W. Aiman, M. Qirem, Osama Alkhlaifat, Jose García, Ummul Z Asfeen, Samer Jumean, M. Rayad, S. Veeraballi, T. DaCosta, G. Guron, H. Shaaban   +10 more
semanticscholar   +1 more source

Efficacy and safety of encorafenib-based regimens in colorectal cancer: A systematic review of clinical trials.

Journal of Clinical Oncology, 2023
e15600 Background: BRAF gene mutation is present in 10% of the world’s 3rd common cancer, i.e., colorectal cancer (CRC). Constitutive activation of the mitogen-activated protein kinase pathway (MAPKP) results from this mutation, abnormal activation of ...
W. Aiman, Samer Jumean, Jose García, Ummul Z Asfeen, Osama Alkhlaifat, M. Qirem, M. Rayad, A. Ahmad, T. DaCosta, G. Guron, H. Shaaban   +10 more
semanticscholar   +1 more source

Protein expression of KIT, BRAF, GNA11, GNAQ and RASSF1 in feline diffuse iris melanomas.

The Veterinary Journal, 2019
Feline iris melanoma, the most common feline intraocular tumour, has a reported metastatic rate of 19-63%. However, there is a lack of knowledge about its molecular biology.
J. G. Rushton, M. Korb, Stefan Kummer, U. Reichart, A. Fuchs‐Baumgartinger, A. Tichy, B. Nell   +6 more
semanticscholar   +1 more source

Quail neuroretina c-Rmil(B-raf) proto-oncogene cDNAs encode two proteins of 93.5 and 95 kDa resulting from alternative splicing.

Oncogene, 1992
c-Rmil is the cellular allele of the v-Rmil oncogene transduced during in vitro passaging of Rous-associated virus type 1 in chicken embryonic neuroretina (NR) cells. The c-Rmil proto-oncogene is the avian homolog of the mammalian B-raf gene and belongs to the mil/raf oncogene family of serine/threonine protein kinases.
A, Eychène, J V, Barnier, P, Dézélée, M, Marx, D, Laugier, I, Calogeraki, G, Calothy   +6 more
openaire   +1 more source

Genomic organization and nucleotide sequence of the coding region of the chicken c-Rmil(B-raf-1) proto-oncogene.

Biochemical and Biophysical Research Communications - BBRC, 1993
I. Calogeraki, J. Barnier, A. Eychène, M. Felder, G. Calothy, M. Marx   +5 more
semanticscholar   +1 more source

Aberrant B-Raf signaling in human cancer -- 10 years from bench to bedside.

Critical reviews in oncogenesis, 2012
Michael Röring, T. Brummer
semanticscholar   +1 more source

Solid-state 31P NMR spectroscopy of precipitated guanine nucleotide-binding protein Ras in complexes with its effector molecules Raf kinase and RalGDS.

Journal of Physical Chemistry B, 2007
C. Ader, M. Spoerner, H. Kalbitzer, E. Brunner   +3 more
semanticscholar   +1 more source

BRAF oncogene in malignant melanoma

, 2012
Jing Li
semanticscholar   +1 more source