EFFECT OF MELATONIN ON PANCREATIC AUTOPHAGY IN RATS WITH GESTATIONAL DIABETES MELLITUS AND THE MECHANISM [PDF]
Objective To investigate the effect of melatonin on pancreatic autophagy in rats with gestational diabetes mellitus (GDM) and the underlying mechanism.
ZHENG Qingqing, LI Chao, LI Yan, QIAO Binglong, MA Chunling
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PROTECTIVE EFFECT OF REMIMAZOLAM ON CEREBRAL NERVES IN A RAT MODEL OF CEREBRAL ISCHEMIA/REPERFUSION INJURY AND ITS MECHANISM [PDF]
Objective To investigate the protective effect of remimazolam on cerebral nerves in a rat model of cerebral ischemia/reperfusion injury and its mechanism.
DUAN Mei, LIU Jia, ZHANG Jing, SUN Xiaoli, WANG Shilei
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Notch: From fly wings to human hematological tumors [PDF]
Notch history begins in 1919 with Thomas Hunt Morgan studies on fruit fly mutants. From then, this gene aroused lively interest in the scientific community since it is involved in a wide variety of processes, including morphogenesis, tissue homeostasis ...
Mirandola Leonardo +5 more
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Effect and mechanism of Juluo decoction combined with Ruhe powder in treatment of rat model of hyperplasia of mammary glands [PDF]
Objective To investigate the effect and mechanism of Juluo Decoction combined with Ruhe Powder in the treatment of rat model of hyperplasia of mammary glands.
NIE Weihong, LIU Hongxi, SUN Guoxin, LIU Chengcong, ZOU Xiao
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Inhibition of Ultraviolet B-induced Apoptosis in Fibroblasts by Human Umbilical Cord Blood Mesenchymal Stem Cell Conditioned Media via the Phosphatidylinositol-3-Kinase/Akt Pathway [PDF]
Background: Ultraviolet B (UVB) irradiation induces photoaging and apoptosis in various cell types. Inhibition of UVB-induced apoptotic pathways has been explored in different apoptotic cascades.
Ferry Sandra +6 more
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Effect of minocycline on cognitive dysfunction in mice with intracerebral hemorrhage and its mechanism [PDF]
Objective To investigate the effect of minocycline (Mcy) on cognitive dysfunction in mice with intracerebral hemorrhage (ICH) and its mechanism. Methods Male C57BL/6J mice were randomly divided into groups A, B, C, D, and E, with 20 mice in each group ...
LI Yangyang, FANG Jian, WANG Xiaoxue
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Effect of Wuzhuyu Decoction on alcoholic gastric ulcer and its mechanism [PDF]
Objective To investigate the effect of Wuzhuyu Decoction (WZYD) on alcoholic gastric ulcer and its mechanism. Methods A total of 120 female KM mice, aged 8 weeks, were randomly divided into normal control group (group A), model control group (group B ...
GAO Ruiyang, LI Jingyao, LI Pingxiang, GE Keli
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Effect of anlotinib on the proliferation and invasion of human lung squamous cell carcinoma NCI-H226 cells and its mechanism [PDF]
Objective To investigate the effect of anlotinib on the proliferation, migration, invasion, and epithelial-me-senchymal transition (EMT) of human lung squamous cell carcinoma NCI-H226 cells.
ZHAO Zhenbo, MA Shengxi, LIU Deyi
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Insulin stimulation of Akt/PKB phosphorylation in the placenta of preeclampsia patients
CONTEXT AND OBJECTIVE: Preeclampsia is a multi-systemic disease and one of the most frequent severe health problems during pregnancy. Binding of insulin triggers phosphorylation and activates cytoplasmic substrates such as phosphatidylinositol 3 kinase ...
Gustavo Dias Ferreira +6 more
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Signal Transduction Mechanisms of Focal Adhesions: Src and FAK-Mediated Cell Response
Cell-to-substrate adhesion sites, also known as focal adhesion sites (FAs), are complexes of different proteins on the cell surface. FAs play important roles in communication between cells and the extracellular matrix (ECM), leading to signal ...
Kazuo Katoh
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