Results 61 to 70 of about 72,845 (194)
C-terminal binding proteins: Emerging roles in cell survival and tumorigenesis [PDF]
, 2006 Within a cell, the levels and activity of multiple pro- and anti-apoptotic molecules act in concert to regulate commitment to apoptosis. Whilst the balance between survival and death can be tipped by the effects of single molecules, cellular apoptosis ...
Blaydes, J.P. +3 more
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Photochemistry and Photobiology, EarlyView.Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza +4 more
wiley +1 more source
, 2010 Recent improvements in molecular sub typing of Non Hodgkin’s lymphomashave resulted in targeted therapies becoming incorporated into treatmentparadigms.
Nolan, David Francis Luke
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Periodontology 2000, EarlyView.Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng +4 more
wiley +1 more source
, 2007 Summary The work described in this thesis focuses on the characterization of the mechanism(s) underlying the deregulated activation of the intrinsic or mitochondrial apoptotic pathway in non-small cell lung cancer (NSCLC) cells.
Checinska, A.
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Signaling through CD44 affects cell cycle progression and c-Jun expression in acute myeloid leukemia cells [PDF]
, 2004 We present here the first evidence linking CD44 signaling to c-Jun expression and cell cycle progression in myeloid cell line models. CD44 ligation with the anti-CD44 monoclonal antibodies have been shown to induce differentiation and inhibit the ...
Abdul Ali Peer Zada +1 more
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Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing
The Journal of Physiology, EarlyView.Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda +5 more
wiley +1 more source
A yeast gene encoding a protein homologous to the human c-has/bas proto-oncogene product
, 1983 Organisms amenable to easy genetic analysis should prove helpful in assessing the function of at least those proto-oncogene products which are highly conserved in different eukaryotic cells.
Sander, C., Donath, C., Gallwitz, D.
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Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman +2 more
wiley +1 more source
Importância da investigação de proteínas de resistência ABCB1, ABCC1 e LRP e da proteína antiapoptótica Bcl-2 no diagnóstico e no prognóstico de leucemias agudas [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2010A resistência a múltiplas drogas é uma das maiores causas para a falha do tratamento das leucemias ...
Moraes, Ana Carolina Rabello de
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