Common tissue-specific expressions and regulatory factors of c-KIT isoforms with and without GNNK and GNSK sequences across five mammals. [PDF]
Goto R, Sakamoto N, Awazu A.
europepmc +1 more source
TAM pathway proteins as novel salivary biomarkers for periodontitis
Abstract Background The identification of molecular biomarkers that help clinicians in early diagnosis is a key focus of periodontal research. The major aim of this cross‐sectional observational study was to assess whether salivary TAM pathway protein levels have the potential to discriminate between periodontally healthy or gingivitis controls and ...
Karina Mendes +7 more
wiley +1 more source
Targeting cell cycle in leukemia: "Is palbociclib the game-changer?": A review. [PDF]
Azizan MA +7 more
europepmc +1 more source
ABSTRACT This study investigated the mechanism of miR‐127‐3p in tumor cell stemness and docetaxel (DTX) resistance in triple‐negative breast cancer (TNBC). hsa‐miR‐127‐3p and KIF3B levels were predicted using databases and validated in TNBC and paracancerous tissues.
Zi‐Chao He, Jun‐Jie Zhao, Ting Yan
wiley +1 more source
GANT61 suppresses proliferation and induces apoptosis in ALK-Positive anaplastic large cell lymphoma via modulating the Hh-PIK3IP1-Akt signaling axis. [PDF]
Chen H +5 more
europepmc +1 more source
ABSTRACT Non‐small cell lung cancer (NSCLC) is the most common type of lung cancer, with a 5‐year survival rate of less than 20% and a high risk of recurrence despite advances in treatment. This study aimed to identify new therapeutic targets to increase the effectiveness of NSCLC treatments.
Rui‐Shi Wei +5 more
wiley +1 more source
Exploring the mechanism of plasticizers action in liver damage based on network toxicology, molecular docking, and molecular dynamic simulation. [PDF]
Feng C +7 more
europepmc +1 more source
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu +5 more
wiley +1 more source
Primary malignant melanoma of the lung with C-KIT mutation and SRD5A3-KIT fusion. [PDF]
Shen L +5 more
europepmc +1 more source
Liver Steatosis in Induced Hepatocytes From Carriers of Spinal Muscular Atrophy
ABSTRACT Introduction/Aims Although classically characterized as a motor neuron disease, spinal muscular atrophy (SMA) is increasingly recognized as a multisystem disorder. We previously showed hepatocyte‐intrinsic steatosis in SMA, raising the question of whether SMA carriers, who are typically asymptomatic, may also exhibit subclinical hepatic ...
Lingyu Sun +15 more
wiley +1 more source

