Results 171 to 180 of about 207,584 (200)

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Quercetin Regulates Autophagy to Inhibit PRRSV Replication Through the PI3K/Akt/mTOR Signaling Pathway. [PDF]

Viruses
Yang Y, Li X, Shi H, Yu J, Gao C, Liu Y, Feng W, Peng L, Fu B, Yi P.   +9 more
europepmc   +1 more source

LAT1/SLC7A5‐mediated amino acid uptake is regulated by redox signals triggered by formyl‐peptide receptor 2

The FEBS Journal, EarlyView.
FPR2 activation mediates NOX‐dependent LAT1 expression and, in turn, promotes mTORC1 signaling. Upon stimulation with WKYMVm, the FPR2‐NOX2‐ROS axis upregulates LAT1 via increased c‐Myc phosphorylation and decreased miR‐126. Additionally, it promotes CD98 translocation to the plasma membrane.
Myrhiam Cassese, Chiara Brignola, Stefano Marrone, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo   +5 more
wiley   +1 more source

SOX2 confers tumour permissiveness in a specific skin progenitor population. [PDF]

Nat Commun
Centeno PP, Chester C, Kanellos G, Ford CA, Cammareri P, Inman GJ, Jamieson T, Ridgway RA, Marais R, Campbell AD, Sansom OJ.   +10 more
europepmc   +1 more source

Network pharmacology combined with ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry method to explore the mechanism of Shizhi Fang in treating uric acid nephropathy mice. [PDF]

J Tradit Chin Med
Feng Y, Xuming Z, Zhiyuan WU, Jiandong G.   +3 more
europepmc   +1 more source

SCAMP3-Driven Regulation of ERK1/2 and Autophagy Phosphoproteomics Signatures in Triple-Negative Breast Cancer. [PDF]

Int J Mol Sci
Morales-Cabán BM, Cantres-Rosario YM, Tosado-Rodríguez EL, Roche-Lima A, Meléndez LM, Boukli NM, Suarez-Arroyo IJ.   +6 more
europepmc   +1 more source

3-O-acetylrubiarbonol B preferentially targets EGFR and MET over rubiarbonol B to inhibit NSCLC cell growth. [PDF]

PLoS One
Nam AY, Joo SH, Lee NY, Yoon G, Park JW, Na M, Shim JH.   +6 more
europepmc   +1 more source

Study on the design, synthesis and activity of MDM2/MDMX anti-tumor stapled peptide PROTAC. [PDF]

Sci Rep
Liao X, Guo M, Hu D, Su C, Liao H.
europepmc   +1 more source

Proto oncogene protein C kit inhibitors

Reactions Weekly, 2020
semanticscholar   +3 more sources