Correlation of long interspersed element-1 open reading frame 1 and c-Met proto-oncogene protein expression in primary and recurrent colorectal cancers [PDF]
Kosin Medical Journal, 2022 Background Colorectal cancer is one of the most common cancers worldwide. Colorectal cancer that has recurred and metastasized to other organs also has a very poor prognosis.
Kyung-Yoon Jeon +6 more
doaj +5 more sources
Induction of c-Met Proto-Oncogene by Epstein-Barr Virus Latent Membrane Protein-1 and the Correlation with Cervical Lymph Node Metastasis of Nasopharyngeal Carcinoma [PDF]
The American Journal of Pathology, 2001 Nasopharyngeal carcinoma (NPC) is distinctive in head and neck carcinomas for its close association with Epstein-Barr virus and its highly metastatic nature. Up-regulation of cell motility is essential for enhancement of metastatic potential. The expression of c-Met proto-oncogene, a high-affinity receptor for hepatocyte growth factor/scatter factor ...
Hajime Takeshita +5 more
openaire +4 more sources
MET alterations and therapeutic strategies in non-small cell lung cancer
陆军军医大学学报, 2022 Mesenchymal to epithelial transition factor (MET) often plays a crucial role in cell homeostasis, motility and apoptosis, while its alterations can promote the proliferation, invasion and metastasis of tumors cells. In non-small cell lung cancer (NSCLC),
LI Jian, LU Shun
doaj +1 more source
Frontiers in Medicine, 2023 Melanoma is known to be a radioresistant cancer. Melanoma radioresistance can be due to several factors such as pigmentation, antioxidant defenses and high Deoxyribonucleic acid (DNA) repair efficacy.
Malak Sabbah +10 more
doaj +1 more source
Expression of c-MET in Invasive Meningioma [PDF]
Journal of Pathology and Translational Medicine, 2015 Background: Meningiomas show high recurrence rates even after curative tumor removal. The invasiveness of meningiomas may contribute to their high recurrence rates.
Sumi Yun +5 more
doaj +1 more source
Frontiers in Immunology, 2023 ObjectiveThis study sought to assess the efficacy and safety of immunotherapy combined with single-agent chemotherapy as a second- or later-line setting for metastatic non-small cell lung cancer (NSCLC) and to provide clinical evidence for this treatment
Dongna Chen +10 more
doaj +1 more source
Overexpression of an activated REL mutant enhances the transformed state of the human B-lymphoma BJAB cell line and alters its gene expression profile [PDF]
, 2009 The human REL proto-oncogene encodes a transcription factor in the nuclear factor (NF)-kappaB family. Overexpression of REL is acutely transforming in chicken lymphoid cells, but has not been shown to transform any mammalian lymphoid cell type.
Chin, M. +4 more
core +5 more sources
Maternal recognition of pregnancy in the horse : are MicroRNAs the secret messengers? [PDF]
, 2020 The signal for maternal recognition of pregnancy (MRP) has still not been identified in the horse. High-throughput molecular biology at the embryo-maternal interface has substantially contributed to the knowledge on pathways affected during MRP, but an ...
Deforce, Dieter +11 more
core +2 more sources
Histopathologic classification and immunohistochemical features of papillary renal neoplasm with potential therapeutic targets [PDF]
Journal of Pathology and Translational MedicineBackground Papillary renal cell carcinoma (pRCC) is the second most common histological subtype of renal cell carcinoma and is considered a morphologically and molecularly heterogeneous tumor.
Jeong Hwan Park +4 more
doaj +1 more source
Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies [PDF]
, 2019 A significantly increased level of the reactive oxygen species (ROS) scavenger glutathione (GSH) has been identified as a hallmark of renal cell carcinoma (RCC). The proposed mechanism for increased GSH levels is to counteract damaging ROS to sustain the
Meierhofer, David, Xiao, Yi
core +2 more sources