Correlation of long interspersed element-1 open reading frame 1 and c-Met proto-oncogene protein expression in primary and recurrent colorectal cancers [PDF]
Kosin Medical Journal, 2022 Background Colorectal cancer is one of the most common cancers worldwide. Colorectal cancer that has recurred and metastasized to other organs also has a very poor prognosis.
Kyung-Yoon Jeon +6 more
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MET alterations and therapeutic strategies in non-small cell lung cancer
陆军军医大学学报, 2022 Mesenchymal to epithelial transition factor (MET) often plays a crucial role in cell homeostasis, motility and apoptosis, while its alterations can promote the proliferation, invasion and metastasis of tumors cells. In non-small cell lung cancer (NSCLC),
LI Jian, LU Shun
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Frontiers in Medicine, 2023 Melanoma is known to be a radioresistant cancer. Melanoma radioresistance can be due to several factors such as pigmentation, antioxidant defenses and high Deoxyribonucleic acid (DNA) repair efficacy.
Malak Sabbah +10 more
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Expression of c-MET in Invasive Meningioma [PDF]
Journal of Pathology and Translational Medicine, 2015 Background: Meningiomas show high recurrence rates even after curative tumor removal. The invasiveness of meningiomas may contribute to their high recurrence rates.
Sumi Yun +5 more
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Induction of c-Met Proto-Oncogene by Epstein-Barr Virus Latent Membrane Protein-1 and the Correlation with Cervical Lymph Node Metastasis of Nasopharyngeal Carcinoma [PDF]
The American Journal of Pathology, 2001 Nasopharyngeal carcinoma (NPC) is distinctive in head and neck carcinomas for its close association with Epstein-Barr virus and its highly metastatic nature. Up-regulation of cell motility is essential for enhancement of metastatic potential. The expression of c-Met proto-oncogene, a high-affinity receptor for hepatocyte growth factor/scatter factor ...
T, Horikawa +5 more
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Frontiers in Immunology, 2023 ObjectiveThis study sought to assess the efficacy and safety of immunotherapy combined with single-agent chemotherapy as a second- or later-line setting for metastatic non-small cell lung cancer (NSCLC) and to provide clinical evidence for this treatment
Dongna Chen +10 more
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Methods and compositions for stimulating T-lymphocytes [PDF]
, 2003 Disclosed are methods, compositions, antibodies, and therapeutic kits for use in stimulating cytotoxic T-lymphocytes and generating immune responses against epitopes of protooncogenes.
Fisk, Bryan A. +2 more
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Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies [PDF]
, 2019 A significantly increased level of the reactive oxygen species (ROS) scavenger glutathione (GSH) has been identified as a hallmark of renal cell carcinoma (RCC). The proposed mechanism for increased GSH levels is to counteract damaging ROS to sustain the
Meierhofer, David, Xiao, Yi
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Histopathologic classification and immunohistochemical features of papillary renal neoplasm with potential therapeutic targets [PDF]
Journal of Pathology and Translational MedicineBackground Papillary renal cell carcinoma (pRCC) is the second most common histological subtype of renal cell carcinoma and is considered a morphologically and molecularly heterogeneous tumor.
Jeong Hwan Park +4 more
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Wnt/beta-catenin/Tcf signaling: A critical pathway in gastrointestinal tumorigenesis [PDF]
, 2002 Cancers of the gastrointestinal tract, including the liver, bile ducts, and pancreas, constitute the largest group of malignant tumors. Colorectal cancer is one of the most common neoplastic diseases in Western countries and one of the leading causes of ...
Bommer, G., Göke, B., Kolligs, F. T.
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