Results 101 to 110 of about 45,592 (164)

A Clinical Guidance for the Management of Patients With Hepatoid Adenocarcinoma and A Case Series

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor of non‐germ cell origin that morphologically resembles hepatocellular carcinoma (HCC). HAC has a propensity to metastasize to the liver and therefore may be mistaken for HCC. There is a lack of standardized treatment protocols, and further studies are needed to evaluate the benefit of ...
Christina Liava, Sudhakar Venkatesh, Michael S. Torbenson, Patrick S. Kamath, Moira Hilscher   +4 more
wiley   +1 more source

Pharmacovigilance analysis of vision disorders relating to brimonidine treatment and mechanism study using network toxicology and molecular docking. [PDF]

Sci Rep
Xu L, Zhao S, Zhao S, Wang Z, Fang J, Cai C, Wang J.   +6 more
europepmc   +1 more source

Efficacy of Topical Beta‐Blockers in Managing Epidermal Growth Factor Receptor Inhibitor‐Related Paronychia and Pyogenic Granuloma‐Like Lesion: A Systematic Review and Meta‐Analysis

Cancer Medicine, Volume 15, Issue 2, February 2026.
The meta‐analysis, involving with 96 patients, shows high overall response rate with favorable safety to use topical beta‐blockers for epidermal growth factor receptor inhibitors‐induced periungual side effects. Subgroups of lung cancer or solution formation had lower complete response rate, while tyrosine kinase inhibitor and female patients had ...
Po‐Kai Chan, Wei‐Ting Yen, Po‐Huang Chen   +2 more
wiley   +1 more source

PTEN loss and ERBB2/ERBB3-mediated AKT reactivation drive resistance to MET inhibition in MET-amplified hepatocellular carcinoma. [PDF]

Cell Oncol (Dordr)
Qian R, Guo Y, Hu X, Ling J, Geng H, Ye Q, Zhang L, Zhan S, Liao L, Ge Y, Zheng Q, Cao Y.   +11 more
europepmc   +1 more source

Metformin‐Mediated Glycaemic Regulation as a Potential Strategy for Breast Cancer Prevention

Cancer Medicine, Volume 15, Issue 2, February 2026.
Metformin (MET), a common antihyperglycemic drug, shows promising anti‐cancer effects in breast cancer (BC). It activates adenosine monophosphate‐activated protein kinase (AMPK), regulating cellular energy and inducing cell cycle arrest, anti‐proliferation, and microenvironment alterations.
Ambulugala Gamage Rajika Greshamali Jinadasa, N. D. Amal Wageesha, Sameera R. Samarakoon, Sagarika Ekanayake, H. M. Kasuni Akalanka   +4 more
wiley   +1 more source

Overexpressed MET drives aggressive thyroid cancer phenotypes and serves as a precision therapeutic target. [PDF]

Sci Rep
Xu R, Wan Y, Ding B.
europepmc   +1 more source

Digital Biomarkers for Precision Early Detection of Lung Cancer: Integrating AI‐Driven Multi‐Omics Into Clinical Pathways

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley   +1 more source

Challenges and Limitations of Sequential MET-TKI Therapy in METex14- Positive NSCLC With a Focus on Non-ILD Toxicities: A Case Report. [PDF]

Cancer Rep (Hoboken)
Nigi A, Kumasa T, Iwamoto K, Itani H, Kondou S, Uraki J.   +5 more
europepmc   +1 more source

Incorporating Scale Uncertainty into Differential Expression Analyses Using ALDEx2

Current Protocols, Volume 6, Issue 2, February 2026.
Abstract Differential abundance or expression analyses are routinely performed on metagenomic, metatranscriptomic, and amplicon sequencing data. In such datasets, analysts usually have no information regarding the true scale (i.e., size) of the microbial community or sample under study, with inter‐sample differences in sequencing depth instead being ...
Scott J. Dos Santos, Gregory B. Gloor
wiley   +1 more source

Single-cell analysis of heterogeneity in reverted hiPSC-derived human hepatic stellate cells. [PDF]

JHEP Rep
Wang X, Ha EH, Bian L, Feng Z, Zhang F, O'Shaughnessy K, Wang L, Hochwald A, Zheng Y, Chen W, Zhang Y, Wu X.   +11 more
europepmc   +1 more source