Results 151 to 160 of about 49,807 (253)

Unraveling the proteomic signatures of coronary artery disease and hypercholesterolemia. [PDF]

Biomol Biomed
Anlar GG, Pedersen S, Al Ashmar S, Krzyslak H, Kamareddine L, Zeidan A.   +5 more
europepmc   +1 more source

Shorter Telomeres and Faster Telomere Attrition in Individuals With Five Syndromic Forms of Intellectual Disability: A Systematic Review and Meta‐Analysis

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background People with intellectual disability suffer complex challenges due to adaptive functioning limitations, high rates of chronic diseases and shortened lifespans compared with the general population. Telomere shortening is a hallmark of ageing, and short telomeres are linked to neurological disorders.
Sarah M. Hanley, Nicola S. Schutte, Jessica Bellamy, Joshua Denham   +3 more
wiley   +1 more source

Precision medicine: an intrahepatic cholangiocarcinoma with a novel RBPMS-MET fusion sensitive to crizotinib. [PDF]

Oncologist
Wan W, Liu X, Zhang Y, Shen R, Xia W, Li S, Tan Y, Duan Q, Liu J, Wang W.   +9 more
europepmc   +1 more source

Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari, Johnson Ung, Jeffrey W. Craig, Kallesh D. Jayappa, Ipsita Pal, David J. Feith, Thomas P. Loughran Jr, Owen A. O’Connor   +7 more
wiley   +1 more source

Non-small cell lung cancer and the tumor microenvironment: making headway from targeted therapies to advanced immunotherapy. [PDF]

Front Immunol
De Lucia A, Mazzotti L, Gaimari A, Zurlo M, Maltoni R, Cerchione C, Bravaccini S, Delmonte A, Crinò L, Borges de Souza P, Pasini L, Nicolini F, Bianchi F, Juan M, Calderon H, Magnoni C, Gazzola L, Ulivi P, Mazza M.   +18 more
europepmc   +1 more source

A strategy for multimodal integration of transcriptomics, proteomics, and radiomics data for the prediction of recurrence in patients with IDH‐mutant gliomas

International Journal of Cancer, Volume 157, Issue 3, Page 573-587, 1 August 2025.
What's new? Isocitrate dehydrogenase (IDH)‐mutant gliomas typically affect young adults and invariably progress toward increasingly malignant phenotypes, despite treatment. Recurrence often is unpredictable, however, indicating a need for a deeper understanding of factors that drive disease return.
Tiffanie Chouleur, Christèle Etchegaray, Laura Villain, Antoine Lesur, Thomas Ferté, Marco Rossi, Laetitia Andrique, Costanza Simoncini, Anne‐Sophie Giacobbi, Matteo Gambaretti, Egesta Lopci, Bethania Fernades, Gunnar Dittmar, Rolf Bjerkvig, Boris Hejblum, Rodolphe Thiébaut, Olivier Saut, Lorenzo Bello, Andreas Bikfalvi   +18 more
wiley   +1 more source

Footprint-free induced pluripotent stem cells can be successfully differentiated into mesenchymal stromal cells in the feline model. [PDF]

Stem Cell Res Ther
Weeratunga P, Harman RM, Jager MC, Van de Walle GR.   +3 more
europepmc   +1 more source

Molecular characterisation of ret tyrosine kinase signalling [PDF]

, 2005
Arighi, Elena
core  

Human sporadic breast carcinoma histotypes driven by the Human Betaretrovirus homologous to Mouse Mammary Tumor Virus

International Journal of Cancer, Volume 157, Issue 2, Page 371-383, 15 July 2025.
What's new? While estrogens, obesity, and alcohol are recognized risk factors for breast cancer, a viral hypothesis has been suggested based on the murine model of Mouse Mammary Tumor Virus (MMTV)‐induced mammary tumors. This study analyzed sequences of the human homolog of MMTV across human breast carcinoma histotypes, detecting the virus in all types
Prospero Civita, Chiara Maria Mazzanti, Francesca Lessi, Caterina Marchiò, Cristian Scatena, Michele Menicagli, Matteo Ghilli, Manuela Roncella, Antonio Giuseppe Naccarato, Anna Sapino, Jacob Hochman, Mauro Pistello, Generoso Bevilacqua   +12 more
wiley   +1 more source

Tepotinib for the Treatment of Lung Adenocarcinoma Harboring MET Y1003N Point Mutation: A Case Report. [PDF]

Thorac Cancer
Umeda Y, Kimura S, Kimura J, Imamura Y, Ishizuka T.   +4 more
europepmc   +1 more source