Results 181 to 190 of about 49,807 (253)

HHLA2 activates c-Met and identifies patients for targeted therapy in hepatocellular carcinoma. [PDF]

J Exp Clin Cancer Res
Huang X, Fang R, Pang Y, Zhang Z, Huang J, Li Y, Yuan T, Zeng Y, Yao Z, Vega-Rubín-de-Celis S, Thinwa J, Zhang Q, Shen H, Wang J, Shen F, Wei Y.   +15 more
europepmc   +1 more source

International Expert Opinion on Standard of Care for Patients With Schinzel‐Giedion Syndrome: A Modified Delphi Study

American Journal of Medical Genetics Part A, Volume 197, Issue 6, June 2025.
ABSTRACT Schinzel‐Giedion Syndrome (SGS) is an ultra‐rare, multisystem, genetic developmental disorder caused by gain‐of‐function pathogenic variants in the SETBP1 gene. No standard of care (SoC) recommendations currently exist. To assess expert opinion on SoC for individuals with SGS using a modified Delphi method.
Jessica Duis, Laura Agresta, William E. Bennett Jr, Henry Chambers, Antonia Clarke, Charlie Fairhurst, Julie Hoover‐Fong, Feilim Murphy, Garey Noritz, Scott Schwantes, Michael Shreve, Kabelo Thusang, Darcy Weidemann, Rebecca Beale, Aditi Mehta, Andrew Wilhelmsen, Nuala Summerfield   +16 more
wiley   +1 more source

Efficacy of chemotherapy plus immune checkpoint inhibitors in patients with non-small cell lung cancer who have rare oncogenic driver mutations: a retrospective analysis. [PDF]

BMC Cancer
Yamaguchi T, Shimizu J, Matsuzawa R, Watanabe N, Horio Y, Fujiwara Y.   +5 more
europepmc   +1 more source

Potential New Expression Biomarkers for Anorexia Nervosa

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 198, Issue 4, June 2025.
ABSTRACT Anorexia nervosa (AN) is a psychiatric disorder with an estimated heritability of around 70%. Although the largest meta‐analysis of genome‐wide association studies on AN identified independent risk‐conferring loci for the disorder, the molecular mechanisms underlying the genetic basis of AN remain to be elucidated.
Camille Verebi, Nicolas Lebrun, Justine Vily Petit, Odile Viltart, Philibert Duriez, Benjamin Saint‐Pierre, Philip Gorwood, Nicolas Ramoz, Thierry Bienvenu   +8 more
wiley   +1 more source

Treatment of non-small cell lung cancer with RET rearrangements. [PDF]

Cancer
Hoe HJ, Solomon BJ.
europepmc   +1 more source

Circulating Tumor Cell Detection for Therapeutic and Prognostic Roles in Breast Cancer

Cancer Medicine, Volume 14, Issue 11, June 2025.
The figure outlines the process of tumor cell migration, the samples available for testing and the classification of enrichment assays, and the use of circulating cells. CSF: cerebrospinal fluid‐derived circulating tumor cell, CTC: circulating tumor cell, CTEC: circulating tumor endothelial cell, DTC: disseminated tumor cell, MRD: minimal residual ...
Saiying Ma, Xiaojia Wang, Peter Ping Lin, Lei Lei   +3 more
wiley   +1 more source

Recent Findings in N6‐Methyladenosine Modification and Significance in Pancreatic Cancer

Cancer Medicine, Volume 14, Issue 11, June 2025.
ABSTRACT Background RNA modifications are widely detected in cells and are involved in RNA structural stabilization and regulation of gene expression. In cancer cells, RNA modifications are altered, resulting in abnormal expression of numerous genes and promoting cancer growth. N1‐methyladenosine (m1A), N6‐methyladenosine (m6A), N3‐methylcytosine (m3C),
Tomoaki Hara, Sikun Meng, Yasuko Arao, Yoshiko Saito, Kana Inoue, Sarah Rennie, Ken Ofusa, Toru Kitagawa, Hideshi Ishii   +8 more
wiley   +1 more source

Translational Advances in Oncogene and Tumor-Suppressor Gene Research. [PDF]

Cancers (Basel)
Stojchevski R, Sutanto EA, Sutanto R, Hadzi-Petrushev N, Mladenov M, Singh SR, Sinha JK, Ghosh S, Yarlagadda B, Singh KK, Verma P, Sengupta S, Bhaskar R, Avtanski D.   +13 more
europepmc   +1 more source

NS3 of hepatitis C virus drives hepatocellular carcinoma progression through a novel RNA‐interference pathway

Journal of Cell Communication and Signaling, Volume 19, Issue 2, June 2025.
Abstract Hepatocellular carcinoma (HCC), a severe consequence of hepatitis C virus infection, is significantly influenced by the virus’s non‐structural protein 3 (NS3). This study employed transcriptome sequencing to explore the role of NS3 in promoting HCC progression by comparing gene expression profiles between HCV‐infected HCC tissues and healthy ...
Yajun Liang, Jian Luo, Liya Hu, Jun Zhang   +3 more
wiley   +1 more source

Prolonged Response to Afatinib and Crizotinib in a Rare Case of EGFR-, HER2-, MET- and ROS1-Alterated Lung Adenocarcinoma. [PDF]

Int J Mol Sci
Plomer E, Früh M, Lauber A, Demmer I, Jochum W, Koster KL.   +5 more
europepmc   +1 more source