Results 1 to 10 of about 15,137 (114)

Expression of C-terminal ALK, RET, or ROS1 in lung cancer cells with or without fusion

BMC Cancer, 2019
Background Genetic alterations, including mutation of epidermal growth factor receptor or v-Ki-ras2 kirsten rat sarcoma viral oncogene homolog and fusion of anaplastic lymphoma kinase (ALK), RET proto-oncogene (RET), or v-ros UR2 sarcoma virus oncogene ...
Koh Furugaki, Marie Mochizuki, Mirei Kohno, Sei Shu, Naoki Harada, Yasushi Yoshimura   +5 more
doaj   +1 more source

A biologia molecular no prognóstico do carcinoma da tireóide

Revista do Colégio Brasileiro de Cirurgiões
This overview examines some selected genetic mechanisms of cancer development. Strong evidence has been accumulated suggesting that alteration in either the struture or activity of proto-oncogene contributes to the development and for the maintenance of ...
Aluizio Soares de Souza Rodrigues
doaj   +1 more source

Mutation of rearranged during transfection (RET) is associated with enhanced tumor immunogenicity and favorable outcomes in pan-cancer immunotherapy. [PDF]

Oncologist
Cai J, Huang Z, Li Y, Zhou J, Xu Y, Cai M, Zhao H, Zhao B.   +7 more
europepmc   +1 more source

Medullary thyroid carcinoma exclusively associated with a homozygous RET V778I pathogenic variant: a case report with review of literature. [PDF]

Endocr J
Kihara M, Miyauchi A, Akamizu T.
europepmc   +1 more source

Precision management of medullary thyroid carcinoma: a dynamic framework integrating biomarkers, genotyping, and risk stratification. [PDF]

Front Endocrinol (Lausanne)
Jia C, Guo S, Wu K, Wang Y, Yang S, Wang L, Chen T, Meng X.   +7 more
europepmc   +1 more source

Protein kinase-related tumors in the pediatric population : Updated review on an emerging group with emphasis on the more rarely involved kinases. [PDF]

Pathologie (Heidelb)
Flucke U, Versleijen-Jonkers YMH, Mentzel T, Mueller AM, Hiemcke-Jiwa LS, Alaggio R.   +5 more
europepmc   +1 more source

Discovery of a Proteolysis Targeting Chimera for TRKA and RET-derived oncoproteins. [PDF]

Sci Rep
Moccia M, Zhang L, Wang Z, Wang M, Federico G, Santoro M, Li HY, Carlomagno F.   +7 more
europepmc   +1 more source

Accurate <i>RET</i> Fusion Detection in Solid Tumors Using RNA Sequencing Coverage Imbalance Analysis. [PDF]

Int J Mol Sci
Gaziev I, Khristichenko A, Luppov D, Suntsova M, Bondarenko E, Reinberg M, Matrosova A, Khilal N, Sorokin M, Sekacheva M, Poddubskaya E, Buzdin A, Zakharova G.   +12 more
europepmc   +1 more source

Sporadic medullary thyroid carcinoma with a rare RET transmembrane domain mutation (A641R) that responds to selpercatinib. [PDF]

Oncologist
Fukuda N, Toda K, Chiba T, Fukada I, Mori S, Tonooka A, Toda E, Yoshida J, Wang X, Oki R, Nakao T, Urasaki T, Nakano K, Ono M, Tomomatsu J, Takeuchi K, Takahashi S, Miura Y.   +17 more
europepmc   +1 more source

Rare cases in two Chinese MEN2A families with RET C634Y germline mutation-a homozygous female patient and heterozygous identical twins: a systematic review of literature. [PDF]

Front Endocrinol (Lausanne)
Qi XP, Weng YT, Chen ZY, Zhang MX, Yang XL, Cao ZL, Zhang XX, Zhu WB, Yu HY, Chen WY, Chen JY, Li FP.   +11 more
europepmc   +1 more source