Translational Oncogenomics and Human Cancer Interactome Networks [PDF]
An overview of translational, human oncogenomics, transcriptomics and cancer interactomic networks is presented together with basic concepts and potential, new applications to Oncology and Integrative Cancer Biology.
I. C. Baianu
core +1 more source
Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]
Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama +4 more
core +1 more source
Crosstalk between cAMP and MAP Kinase Signaling in the Regulation of Cell Proliferation
Hormonal stimulation of cyclic adenosine monophosphate (cAMP) and the cAMP-dependent protein kinase PKA regulates cell growth by multiple mechanisms.
Altschuler +122 more
core +1 more source
Functional regulation of the Neurofibromatosis 2 tumor suppressor merlin [PDF]
Neurofibromatosis 2 (NF2) is an autosomal dominant disorder manifested by the formation of multiple benign tumors of the nervous system. Affected individuals typically develop bilateral vestibular schwannomas which lead to deafness and balance disorders.
Pehrsson, Minja
core
SMURF2 in Anticancer Therapy: Dual Role in Carcinogenesis and Theranostics. [PDF]
Eom J, Chun Y, Chang HR.
europepmc +1 more source
Unraveling the Impact of KRAS Accessory Proteins on Oncogenic Signaling Pathways. [PDF]
Garg V +11 more
europepmc +1 more source
Impact of Co-Mutations and Genetic Variations on Malignancy Risk in RAS-Positive Indeterminate Thyroid Nodules: an Institutional Experience. [PDF]
Wong LQ, Baloch ZW.
europepmc +1 more source
The paradox of cellular senescence in prostate cancer: from tumor suppression to tumor promotion. [PDF]
Xing Y +6 more
europepmc +1 more source
Targeting MET and KRAS G12C co-occurring mutation in metastatic adenoid cystic carcinoma of the trachea: a case report. [PDF]
Zhang L, Wang T, Xu Y, Ji Y, Nie K.
europepmc +1 more source
PrP<sup>C</sup>-Neutralizing Antibody Confers an Additive Benefit in Combination with 5-Fluorouracil in KRAS-Mutant Colorectal Cancer Models, Associated with Reduced RAS-GTP and AKT/ERK Phosphorylation. [PDF]
Lee JK, Yoon JY, Lee JY, Lee SH.
europepmc +1 more source

