Results 331 to 340 of about 228,370 (365)
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Activation of proto-oncogenes: an immediate early event in human cytomegalovirus infection.
Science, 1990A rapid increase in the RNA levels of the proto-oncogenes c-fos, c-jun, and c-myc was detected after human cytomegalovirus infection. Neither inactivation of viral infectivity with ultraviolet irradiation (with or without psoralen), nor inhibition of ...
Istran Boldogh +2 more
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Medical Hypotheses, 1988
In reviewing recent literature on activated proto-oncogenes including retroviral infection (without oncogene), translocation and inherited childhood cancer, I have come to the conclusion that activated proto-oncogenes are not involved in development of tumors. There is one exception in which a translocated proto-myc leads to transformation. That is the
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In reviewing recent literature on activated proto-oncogenes including retroviral infection (without oncogene), translocation and inherited childhood cancer, I have come to the conclusion that activated proto-oncogenes are not involved in development of tumors. There is one exception in which a translocated proto-myc leads to transformation. That is the
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American Review of Respiratory Disease, 1990
The development of human lung cancer may require multiple genetic deletions affecting a number of chromosomes, e.g., 1, 3, 11, 13, and 17. These genetic aberrations may induce the activation of proto-oncogenes (c-jun, ras, c-raf1) and the loss of tumor ...
J. Bergh
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The development of human lung cancer may require multiple genetic deletions affecting a number of chromosomes, e.g., 1, 3, 11, 13, and 17. These genetic aberrations may induce the activation of proto-oncogenes (c-jun, ras, c-raf1) and the loss of tumor ...
J. Bergh
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DNA and Cell Biology, 1992
Among environmental pollutants, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; dioxin) is one of the most potent tumor promoters and teratogens known. The molecular mechanisms responsible for the biological activity of TCDD, however, remain largely unknown ...
Alvaro Puga, D. Nebert, France Carrier
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Among environmental pollutants, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; dioxin) is one of the most potent tumor promoters and teratogens known. The molecular mechanisms responsible for the biological activity of TCDD, however, remain largely unknown ...
Alvaro Puga, D. Nebert, France Carrier
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Expression of proto-oncogenes in neural tissues
Brain Research, 1988Several proto-oncogenes have been shown to be expressed in tissues of neural origin. In most cases, their expression is developmentally regulated and they encode proteins similar in their sequence to a variety of known proteins involved in transferring information from the cell surface to the nucleus. Some of the proto-oncogenes, including src and yes,
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Regulation of the vav proto-oncogene by LKLF
Gene, 2001The transcriptional induction of the vav proto-oncogene coincides with the first appearance of the definitive hematopoietic stem cell in the aorta-gonad-mesonephros region. Vav promoter activity was dependent on a previously identified 23 bp DNA segment containing PU.1 and Runx1/AML-1 binding sites and on a newly identified, highly conserved, 12 bp DNA
Rodney S. Kawahara +2 more
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Proto-oncogenes in Drosophila melanogaster
Trends in Genetics, 1987Abstract More than ten different proto-oncogenes have been identified in the genome of Drosophila melanogaster . Their structural characterizations shows a high degree of conservation compared with the corresponding genes in vertebrates, and provides interesting clues to the evolution of proto-oncogenes.
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Proto-oncogenes/ transcription factors
1998Following partial hepatectomy, there is a rapid and highly orchestrated series of biochemical events which occur prior to cellular proliferation. Some of these events are presumably intimately linked with the eventual regeneration of the liver, whereas others are likely to be stress-related or required for the continued differentiated function of the ...
J. K. Westwick, D. A. Brenner
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Proto-oncogenes in pattern formation
Trends in Genetics, 1987There is now a considerable body of evidence suggesting that protoonc~genes are cellular genes whose products play a fundamental role in the proliferation and differentiation of cells. Mutations in these genes convert them to active elements in the cooperative process of tumorigenesis. Specific functions have been assigned to certain proto-uncogenes on
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A Role for Proto-Oncogenes in Differentiation?
1986Ever since the discovery of proto-oncogene products in the normal cell, their biological role and molecular function have been of major interest in molecular and cellular biology. To date more than 30 different c-onc genes are known which encode proteins localized in the nucleus or cytoplasm, are associated with the plasma membrane or even secreted ...
Erwin F. Wagner, Rolf Müller
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