Results 21 to 30 of about 482 (211)

Nacionalismo e racismo [PDF]

open access: yes, 2022
This paper explores the complex and contradictory relationships between nationalism and racism. It aims to show that these two ideological projects have developed distinct and independent trajectories which are based on their intrinsic conceptual ...
Malesevic, Sinisa
core   +1 more source

Divina Mens: Imperial Propaganda in De architectura 6.1 [PDF]

open access: yes, 2023
This paper, framed by “racecraft” theory (Fields and Fields 2012), argues that the first chapter of Book VI of Vitruvius’ De architectura positions the Roman state led by Augustus—established at the temperate middle of the ecumene by the “divine ...
Peart, Alex-Jaden
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Are Our Racial Concepts Necessarily Essentialist Due to Our Cognitive Nature? [PDF]

open access: yes, 2019
Mallon and Kelly claim that hybrid constructionism predicts, at least, that (1) racial representations are stable over time and (2) that racial representations should vary more in mixed-race cultures than in cultures where ...
Bayruns Garcia, Eric
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Addressing the concept and evidence of institutional racism in Irish education [PDF]

open access: yes, 2012
This proceedings document tells a critical story of the event. Using a social and cultural perspective on racism, power and education, it provides a set of questions for ongoing public, policy-maker and research debate.
Curtin, Alicia, Kitching, Karl
core  

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Ireland: from racism without “race” to racism without racists [PDF]

open access: yes, 2009
The Irish have been relentlessly racialized in their diaspora settings, yet little historical work engages with “race” to understand Irish history on the island of Ireland.
Garner, Steve
core   +2 more sources

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