Development and Implementation of a Protocol for In-Room Surgical Procedures in Paediatric Intensive Care. [PDF]
Revel L, Baptista Peixoto Befecadu F.
europepmc +1 more source
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Acute Foot Warming Enhances Plantar Tactile Sensitivity With Limited Postural Control Effects in Obese Older Adults. [PDF]
Machado MS +5 more
europepmc +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Does Test Duration Matter? Comparing 1-s and 5-s Isometric Mid-Thigh Pull Protocols for Performance Diagnostics in Basketball Players. [PDF]
Xu S +9 more
europepmc +1 more source
Perpetual protocols / Protocoles perpétuels
openaire +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Acute changes in gastrocnemius muscle stiffness following different work-rest calf-raise protocols and percussive therapy: A randomized crossover experimental study. [PDF]
Eken Ö, Çiftçi R, Aldhahi MI.
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Therapeutic Exercise Protocol During Hospitalization in Pediatric Oncohematological Patients: Randomized Clinical Trial. [PDF]
Carniel CF +4 more
europepmc +1 more source

