Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Correction: Personalized versus fixed tactile cueing in Parkinson's disease: Protocol for a randomized controlled trial on gait automaticity. [PDF]
PLOS One Staff.
europepmc +1 more source
EnergyPlus-MCP: A model-context-protocol server for ai-driven building energy modeling
Li Han, Yujie Xu, Tianzhen Hong
openalex +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
An Ecological Momentary Assessment Protocol to Measure Stress, Socialization, and Other Contributors to Smoking Behaviors Among LGBTQ+ Adolescents: Multimethod Evaluation of Feasibility, Acceptability, and Appropriateness From the Puff Break Research Study. [PDF]
Salgin L +9 more
europepmc +1 more source
Innovative Fast‐Charging Protocol Incorporating Proactive Lithium‐Plating Suppression Pulses for Lithium‐Ion Batteries: Protocol Design, Validation, and Post‐Mortem Analysis [PDF]
Ye Ji Ha +9 more
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Decentralized Blockchain-Based Authentication and Interplanetary File System-Based Data Management Protocol for Internet of Things Using Ascon [PDF]
Hiba Belfqih, Abderrahim Abdellaoui
openalex +1 more source

