Results 51 to 60 of about 1,023 (167)

Distribution of Growth-inhibitory Activity, Mineral Contents, and Functional Components in Different Tissue Parts of Asparagus (Asparagus officinalis L.) and Availability of Unusable Parts

open access: yesHortScience, 2021
Asparagus is a popular vegetable rich in healthy functional components. However, the process of its production leaves ferns from aboveground parts and roots from underground parts as unusable parts, and this is an issue to be resolved.
Satoru Motoki   +4 more
doaj   +1 more source

Crystal-associated cholangiopathy in sheep grazing Brachiaria decumbens containing the saponin protodioscin Colangiopatia associada a cristais em ovinos alimentados com Brachiaria decumbens que contém a saponina protodioscina

open access: yesPesquisa Veterinária Brasileira, 2007
An outbreak of hepatogenous photosensitization is reported in a flock of 28 sheep grazing Brachiaria decumbens in Mato Grosso do Sul State, Central-Western Brazil. Seven lambs and an adult sheep were affected and 6 of them died.
Karine B. Brum   +4 more
doaj   +1 more source

A Novel Cytotoxic Steroidal Saponin from the Roots of Asparagus cochinchinensis

open access: yesPlants, 2021
A new steroidal saponin, 26-O-β-d-glucopyranosyl-(25R)-furost-5-ene-3β,22α,26-triol 3-O-(1−4)-β-d-glucopyranosyl-α-l-rhamnopyranosyl-(1−2)-[α-l-rhamnopyranosyl-(1−4)]-β-d-glucopyranoside [asparacochioside A (1)] was isolated from a hot water extract of ...
Ji-Young Kim   +4 more
doaj   +1 more source

Facile Conversion of Spirostan Saponin into Furostan Saponin:  Synthesis of Methyl Protodioscin and Its 26-Thio-analogue

open access: yes, 2016
A facile approach for the conversion of a spirostan saponin into its furostan counterpart, as illustrated by the transformation of dioscin to methyl protodioscin (and its 26-thio-analogue), has been ...
Biao Yu (1466188), Ming Li (91180)
core   +2 more sources

Total Synthesis of Methyl Protodioscin:  A Potent Agent with Antitumor Activity

open access: yes, 2016
Methyl protodioscin (1), otherwise known as 3-O-[α-l-rhamnopyranosyl-(1→2)-{α-l-rhamnopyranosyl-(1→4)}-β-d-glucopyranosyl]-26-O-[β-d-glucopyranosyl]-22-methoxy-25(R)-furost-5-ene-3β,26-diol, has been synthesized for the first time from diosgenin through ...
Qian L. Wang (3032274)   +9 more
core   +2 more sources

Phytochemical study of Tribulus Terrestris L.

open access: yesФармация и фармакология (Пятигорск), 2020
Tríbulus terrestris L., an annual herb belonging to the Zygophyllaceae family and growing in moderate and tropical climates, has a rich chemical composition of biologically active substances and chemical elements.The aim of the work is a phytochemical ...
A. Affaf   +6 more
doaj   +1 more source

Machine Learning‐Guided Identification of Madecassoside as a Potential RAD51 Modulator That Sensitizes Breast Cancer Cells to Cisplatin

open access: yesChemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
Madecassoside was selected from an in‐house natural product library through machine learning‐based virtual screening and identified as a potential modulator of RAD51‐mediated DNA repair that enhances cisplatin sensitivity in breast cancer cells. ABSTRACT Homologous recombination (HR) is an essential pathway for preserving the genomic stability of cells
Minju Oh, Mi‐Young Jeong, Jiwon Choi
wiley   +1 more source

Assessment of Sedative Activity of Protodioscin: In Vivo Approach Along With Receptor Binding Affinity and Molecular Interaction With GABAergic System

open access: yesProgress in Neurology and Psychiatry, Volume 30, Issue 3, August 2026.
ABSTRACT A frequent sleep issue called insomnia can lead to a number of disorders, including despair and anxiety. In order to cure insomnia, this study aims to evaluate the sedative effects of PRO in Swiss mice and use an in silico approach to look into the molecular processes at play. In our investigation, five mice were given oral PRO at doses of 2.5
Rokibul Islam Chowdhury   +7 more
wiley   +1 more source

Morphogenic responses and biochemical alterations induced by the cover crop Urochloa ruziziensis and its component protodioscin in weed species

open access: yes, 2021
Urochloa ruziziensis, a cover plant used in no-till systems, can suppress weeds in the field through their chemical compounds, but the mode of action of these compounds is still unknown.
Baldoqui D. C.   +14 more
core   +1 more source

Sheep poisoning by Panicum dichotomiflorum in northeastern Brazil Intoxicação por Panicum dicotomiflorum em ovinos na região nordeste

open access: yesPesquisa Veterinária Brasileira, 2009
Different species of Panicum, including P. dichotomiflorum,have been reported as a cause of photosensitization in sheep, horses, cattle and goats. An outbreak of hepatogenous photosensitization occurred in 3 flocks of hair sheep in the Brazilian semiarid
Franklin Riet-Correa   +7 more
doaj   +1 more source

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