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Conventional radiation therapy directs photons (X-rays) and electrons at tumours with the intent of eradicating the neoplastic tissue while preserving adjacent normal tissue. Radiation-induced damage to healthy tissue and second malignancies are always a concern, however, when administering radiation.
William P. Levin+3 more
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Ob kirurškem in sistemskem zdravljenju je radioterapija eden od treh stebrov zdravljenja raka. Izjemen tehnološki razvoj na področju pospeševalnikov nabitih delcev je pripeljal do uveljavitve protonske radioterapije kot terapije izbora pri določenih ...
Casar, Božidar, Strojan, Primož
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Proton beam therapy (PBT) is an advanced type of radiotherapy that shows a dosimetric advantage over photon beam therapy and provides superior dose distribution. PBT may improve patient survival by improving the local disease control while reducing toxicity to normal organs, which may result in fewer treatment-related complications.
Marija Popovic-Vukovic+4 more
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Sensitivity analysis of Monte Carlo model of a gantry-mounted passively scattered proton system [PDF]
PURPOSE: This study aimed to present guidance on the correlation between treatment nozzle and proton source parameters, and dose distribution of a passive double scattering compact proton therapy unit, known as Mevion S250.
Baradaran-Ghahfarokhi, Milad+4 more
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Conjunctival melanomas and proton beam therapy [PDF]
Celia Maschi-Cayla+3 more
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Proton beam therapy for liver cancers [PDF]
Proton beam therapy (PBT) delivers less dose to nearby normal organs compared to X-ray therapy (XRT), which is particularly relevant for treating liver cancers given that both mean and low liver dose are among the most significant predictors of radiation induced liver disease (RILD).
Smith Apisarnthanarax+4 more
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Feasibility Study of a Proton Irradiation Facility for Radiobiological Measurements at an 18 MeV Cyclotron [PDF]
A feasibility study of an experimental setup for the irradiation of biological samples at the cyclotron facility installed at the National Centre of Accelerators (Seville, Spain) is presented.
Baratto Roldán, Anna+6 more
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Proton beam therapy for cancer [PDF]
KEY POINTS Radiotherapy is a central modality for treatment of cancer in one-third of cancer patients. It is designed to target tumour cells and damage their DNA, while using advanced shaping techniques such as beam modulation to avoid normal tissues.
Derek S. Tsang, Samir Patel
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Proton-counting radiography for proton therapy: a proof of principle using CMOS APS technology [PDF]
Despite the early recognition of the potential of proton imaging to assist proton therapy (Cormack 1963 J. Appl. Phys. 34 2722), the modality is still removed from clinical practice, with various approaches in development. For proton-counting radiography
D J Parker+19 more
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