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Travel-Time Disparities in Access to Proton Beam Therapy for Cancer Treatment.

JAMA Netw Open
Burus T, VanHelene AD, Rooney MK, Lang Kuhs KA, Christian WJ, McNair C, Mishra S, Paulino AC, Smith GL, Frank SJ, Warner JL.   +10 more
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Proton Beam Therapy

Annual Review of Biophysics and Bioengineering, 1982
Conventional radiotherapy with high energy photons and electrons has been remarkably successful in treating many localized tumors. However, if tumors are large or are located very close to critical normal structures, it becomes very difficult to deliver a tumoricidal dose to the entire tumor volume without compromising the function of these adjacent ...
L J Verhey, J E Munzenrider
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Proton-Beam Therapy in Acromegaly

New England Journal of Medicine, 1968
Abstract Bragg-peak proton hypophysectomy was used in 22 acromegalic patients. Of 14 followed for two to 36 months, size of hands, feet or face decreased in nine. Variable improvement took place in headache, fatigability, heat intolerance, joint pain, sexual function, weight, skin, tachycardia, hypertension, visual fields, glucose tolerance, thyroid ...
Akira Shintani, Andrew G. Frantz, Raymond N. Kjellberg, Bernard Kliman   +3 more
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An introduction to proton beam therapy

British Journal of Hospital Medicine, 2019
Radiotherapy is a highly effective anti-cancer treatment commonly used alongside systemic therapies and surgery to achieve long-term cancer-free survival. Conventional radiotherapy uses photon beams to deliver a high dose of radiation to the tumour volume to eradicate cancer cells.
Ganesh Radhakrishna, Matthew Lowe, Claire L Barker   +2 more
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Proton Beam Radiation Therapy

Cancer Investigation, 2006
All advances in radiation oncology aim to improve the therapeutic ratio for patients. Most of the recent technological advances accomplish this by maximizing dose to the tumor while minimizing dose...
Jay S. Loeffler, Thomas F. DeLaney, Shannon M. MacDonald   +2 more
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Proton Beams in Radiation Therapy

JNCI Journal of the National Cancer Institute, 1992
The rationale for study of proton radiation therapy is that, for some anatomic sites and tumors, the treatment volume is smaller; i.e., there is less irradiation of nontarget tissue while the target is included in three dimensions at each treatment session. As a result, the dose to the target can be raised.
Herman D. Suit, Marcia Urie
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Alanine dosimetry of proton therapy beams

Medical Physics, 1997
An analysis of some of the properties of the ESR-alanine dosimetry in therapeutic proton beams is reported. Thin alanine-based detectors (1 and 2 mm thick pellets and 0.25 mm thick films) were tested in a clinical 62 MeV proton beam. The response of the alanine detectors in unmodulated and modulated proton beams was studied in tissue equivalent ...
ONORI S, D'ERRICO, FRANCESCO, DE ANGELIS C, EGGER E, FATTIBENE P, JANOVSKY I.   +5 more
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Proton Beam Therapy in Liver Malignancies

Current Oncology Reports, 2020
Proton beam therapy (PBT) allows for improved sparing of surrounding normal tissues compared with X-ray-based radiation therapy. This is especially important in the setting of liver malignancies, where an increase in integral dose leads to a higher risk of radiation-induced liver disease (RILD) as well as close proximity to vital gastrointestinal (GI ...
Ariel Pollock, Jason K. Molitoris, Adeel Kaiser, O.M. Siddiqui, Santanu Samanta   +4 more
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Anesthesia for Proton Beam Therapy

2021
Proton beam radiation is being used more frequently to treat malignancies, especially in the central nervous system. Protons have a larger mass than the photons used for standard radiation therapy and therefore can be directed more accurately to the lesion and minimize damage to the surrounding tissue. Although the therapy is not painful, anesthesia is
Kumar G. Belani, David S. Beebe
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