Results 31 to 40 of about 26,002 (260)

Synergistic proton conduction via Ca-vacancy coupled with Li+-bridge in Ca5(PO4)3OH

Communications Materials
Proton conductivity plays a crucial role in the advancement of materials for proton ceramic fuel cells (PCFCs) and a variety of electrochemical devices. Traditional approaches to enhancing proton conductivity in perovskites have largely relied on doping ...
Nabeela Akbar, Qing Pang, Yaokai Lu, Yifu Jing, Manish Singh, Jun Wang, Bin Zhu, Faze Wang, Sining Yun   +8 more
doaj   +1 more source

Proton Conducting Membranes with Molecular Self Assemblies and Ionic Channels for Efficient Proton Conduction

Membranes, 2022
Supramolecular assemblies are vital for biological systems. This phenomenon in artificial materials is directly related to their numerous properties and their performance. Here, a simple approach to supramolecular assemblies is employed to fabricate highly efficient proton conducting molecular wires for fuel cell applications.
Avneesh Kumar, Dong Wook Chang
openaire   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Transport properties of Ba3Ca1+xNb2−xO9−δ composite perovskite oxides

工程科学学报, 2021
ABO3-type perovskite oxides and A3B′B′′2O9-type composite perovskite oxides exhibit proton conduction from 200 ℃ to 1000 ℃. These high-temperature proton conductors have received considerable attention due to their promise as electrolytes in fuel cells ...
Yu-shi DING, Ying LI
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Fabrication and Characterization of Sulfonated Polysulfone Membrane with Different Thicknesses for Proton Exchange Membrane Fuel Cell

Engineering Perspective
Membranes play a critical role in the performance of proton exchange membrane fuel cells. Membrane thicknesses have positive and negative effects on the characteristics of proton exchange membranes.
İrem Tanış, Turan Alp Arslan, Tolga Kocakulak, Gülşen Taşkın, Tuğba Tabanlıgil Calam, Hamit Solmaz   +5 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Proton-Blocking Anion-Exchange Membranes for Efficient Lithium Hydroxide Recovery by Bipolar Membrane Electrodialysis

Membranes
In bipolar membrane electrodialysis (BPED), proton transport through the anion-exchange membrane (AEM) is a major factor that reduces overall process efficiency.
Ji-Hyeon Lee, Moon-Sung Kang
doaj   +1 more source

Enhanced performance of nanocomposite membrane developed on sulfonated poly (1, 4-phenylene ether-ether-sulfone) with zeolite imidazole frameworks for fuel cell application

Scientific Reports, 2023
Proton exchange membrane fuel cells (PEMFC) have received a lot of interest and use metal–organic frameworks (MOF)/polymer nanocomposite membranes. Zeolite imidazole framework-90 (ZIF-90) was employed as an addition in the sulfonated poly (1, 4-phenylene
Bita Soleimani, Ali Haghighi Asl, Behnam Khoshandam, Khadijeh Hooshyari   +3 more
doaj   +1 more source