Results 1 to 10 of about 2,542,698 (234)

Improving proton dose calculation accuracy by using deep learning

Machine Learning: Science and Technology, 2021
Pencil beam (PB) dose calculation is fast but inaccurate due to the approximations when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the most accurate method but it is time consuming.
Chao Wu, Dan Nguyen, Yixun Xing, Ana Barragan Montero, Jan Schuemann, Haijiao Shang, Yuehu Pu, Steve Jiang   +7 more
doaj   +5 more sources

Impact of dose calculation accuracy on inverse linear energy transfer optimization for intensity‐modulated proton therapy

Precision Radiation Oncology, 2023
Objective To determine the effect of dose calculation accuracy on inverse linear energy transfer (LET) optimization for intensity‐modulated proton therapy, and to determine whether adding more beams would improve the plan robustness to different dose ...
Mei Chen, Wenhua Cao, Pablo Yepes, Fada Guan, Falk Poenisch, Cheng Xu, Jiayi Chen, Yupeng Li, Ivan Vazquez, Ming Yang, X. Ronald Zhu, Xiaodong Zhang   +11 more
doaj   +3 more sources

Proton dose calculation on cone-beam computed tomography using unsupervised 3D deep learning networks

Physics and Imaging in Radiation Oncology
Background and Purpose: Poor image quality of cone-beam computed tomography (CBCT) images can hinder proton dose calculation to assess the influence of anatomy changes.
Casper Dueholm Vestergaard, Ulrik Vindelev Elstrøm, Ludvig Paul Muren, Jintao Ren, Ole Nørrevang, Kenneth Jensen, Vicki Trier Taasti   +6 more
doaj   +4 more sources

Parameter Based 4D Dose Calculations for Proton Therapy

Physics and Imaging in Radiation Oncology, 2023
Background and purpose Retrospective log file-based analysis provides the actual dose delivered based on the patient's breathing and the daily beam-delivery dynamics. To predict the motion sensitivity of the treatment plan on a patient-specific basis before treatment start a prospective tool is required.
Markus Stock, Dietmar Georg, Barbara Knäusl   +2 more
exaly   +4 more sources

Calculation of Clinical Dose Distributions in Proton Therapy From Microdosimetry [PDF]

Medical Physics, 2019
PurposeTo introduce a new algorithm—MicroCalc—for dose calculation by modeling microdosimetric energy depositions and the spectral fluence at each point of a particle beam. Proton beams are considered as a particular case of the general methodology.
Alejandro Carabe-Fernandez, Miguel Antonio Cortes-Giraldo, Alejandro Bertolet   +2 more
exaly   +5 more sources

Fast pencil beam dose calculation for proton therapy using a double-Gaussian beam model

Frontiers in Oncology, 2015
The highly conformal dose distributions produced by scanned proton pencil beams are more sensitive to motion and anatomical changes than those produced by conventional radiotherapy.
Joakim eda Silva, Joakim eda Silva, Richard eAnsorge, Rajesh eJena   +3 more
doaj   +3 more sources

Comparing methods to improve cone-beam computed tomography for dose calculations in adaptive proton therapy

Physics and Imaging in Radiation Oncology
Background and purpose: Proton therapy requires dose monitoring, often performed based on repeated computed tomography (reCT) scans. However, reCT scans may not accurately reflect the internal anatomy and patient positioning during treatment.
Casper Dueholm Vestergaard, Nadine Vatterodt, Ulrik Vindelev Elstrøm, Kenneth Jensen, Ole Nørrevang, Ludvig Paul Muren, Stine Sofia Korreman, Vicki Trier Taasti   +7 more
doaj   +3 more sources

Towards implementation of independent calculation-based dose verification in proton therapy.

PLoS ONE
BackgroundProton therapy offers precision in targeting tumors while minimizing damage to surrounding healthy tissues. Independent dose calculation is a secondary dose validation tool for patient-specific quality assurance (PSQA) using Monte Carlo ...
Nichakan Chatchumnan, Mananchaya Vimolnoch, Sakda Kingkaew, Puntiwa Oonsiri, Sornjarod Oonsiri   +4 more
doaj   +4 more sources

A proof-of-concept study of direct magnetic resonance imaging-based proton dose calculation for brain tumors via neural networks with Monte Carlo-comparable accuracy

Physics and Imaging in Radiation Oncology
Background and purpose: Proton therapy currently relies on computed tomography (CT) imaging despite magnetic resonance imaging’s (MRI) superior soft-tissue contrast.
Muheng Li, Carla Winterhalter, Xia Li, Sairos Safai, Antony Lomax, Ye Zhang   +5 more
doaj   +3 more sources

Quantification of Proton Dose Calculation Accuracy in the Lung [PDF]

International Journal of Radiation Oncology*Biology*Physics, 2014
To quantify the accuracy of a clinical proton treatment planning system (TPS) as well as Monte Carlo (MC)-based dose calculation through measurements and to assess the clinical impact in a cohort of patients with tumors located in the lung.A lung phantom and ion chamber array were used to measure the dose to a plane through a tumor embedded in the lung,
Grassberger, Clemens, Daartz, Juliane, Dowdell, Stephen, Ruggieri, Thomas, Sharp, Greg, Paganetti, Harald   +5 more
openaire   +4 more sources