Results 51 to 60 of about 3,212,715 (300)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Analyzing the impact of Temperature on Proton Exchange Membrane Fuel Cell performance Using Matlab

Sukkur IBA Journal of Emerging Technologies, 2018
The Proton Exchange Membrane Fuel cell (PEMFC) is an electrochemical engine that converts the chemical energy of hydrogen into electrical energy. It receives hydrogen at anode and oxygen at the cathode side, due to chemical reaction at electrodes ...
Aftab Ahmed Khuhro
doaj   +1 more source

Studies on the SPEEK membrane with low degree of sulfonation as a stable proton exchange membrane for fuel cell applications [PDF]

Hydrogen, Fuel Cell & Energy Storage, 2017
Sulfonated poly (ether ether ketone) (SPEEK) with a low degree of sulfonation (DS = 40%) was prepared for proton exchange membrane fuel cells (PEMFC).
Mohammad Javad Parnian, Fatemeh Gashoul, Soosan Rowshanzamir   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Polymer membranes for high temperature proton exchange membrane fuel cell : recent advances and challenges

, 2011
Proton-exchange membrane fuel cells (PEMFCs) are considered to be a promising technology for efficient power generation in the 21st century. Currently, high temperature proton exchange membrane fuel cells (HT-PEMFC) offer several advantages, such as high
Thi Xuan Hien Nguyen, Lee, Joong Hee, Kim, Nam Hoon, Bose, S, Lee, JH, Kim, NH, Tapas Kuila, Kin-tak Lau, Nguyen, Thi Xuan Hien, Bose, Saswata, Lau, Kin-tak, Kuila, T, Nam Hoon Kim, Joong Hee Lee, Kuila, Tapas, Saswata Bose, Lau, KT, Hien Nguyen, TX   +17 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

A high conductivity Cs2.5H0.5PMo12O40/polybenzimidazole (PBI)/H3PO4 composite membrane for proton-exchange membrane fuel cells operating at high temperature

, 2008
A high conductivity composite proton-exchange membrane Cs2.5H0.5PMo12O40 (CSPOM)/polybenzimidazole (PBI) for use in hydrogen proton-exchange fuel cells has been prepared. The CsPOM composite membrane is insoluble in water.
邵志刚, Keith Scott, Shao, Zhi-Gang, Scott, Keith, Li, Ming-Qiang, Ming-Qiang Li   +5 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Simulation of PEM Electrolyzer Power Management with Renewable Generation in Owerri, Nigeria

Energies
Proton exchange membrane electrolyzers are an attractive technology for hydrogen production due to their high efficiency, low maintenance cost, and scalability.
MacMatthew C. Ahaotu, Chisom E. Ogbogu, Jesse Thornburg, Isdore Onyema Akwukwaegbu   +3 more
doaj   +1 more source