A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu +10 more
wiley +1 more source
The impact of proton pump inhibitor exposure on pneumonia: an updated meta-analysis based on randomized controlled trials. [PDF]
Wu Z +5 more
europepmc +1 more source
Associations of ambient coarse particulate matter, nitrogen dioxide, and carbon monoxide with the risk of kidney disease: A cohort study [PDF]
Al-Aly, Ziyad +5 more
core +2 more sources
POTENTIAL HARMS OF THE USE OF PROTON PUMP INHIBITORS: DEBATABLE PROBLEMS
Yu. V. Muravyev, O. R. Bobkova
openalex +2 more sources
Ni Single‐Atom Modulation of Ti‐O Covalency Boosts Ammonia Oxidation Electrocatalysis
A Ni single‐atom‐induced enhancement of Ti‐O covalency in Ni SAC@TiO2 generates abundant active sites and promotes selective NHx‐NHy mediated N2 evolution while suppressing poisonous NOx formation, achieving nearly doubled AOR activity with excellent durability.
Subhash Chandra Shit +7 more
wiley +1 more source
Proton pump inhibitor increases intestinal epithelial paracellular permeability via the p38-MAPK/NF-κB signaling pathway. [PDF]
Zhang M +8 more
europepmc +1 more source
The CuNiPc/BiVO4 heterojunction is designed and synthesized for selective CO2 photoreduction. The cascade interfacial Z‐scheme charge transfer and the intramolecular synergy of Cu–Ni dual sites on CO2 activation and H spillover contribute to the high photocatalytic performance and selectivity. ABSTRACT Solar‐driven CO2 conversion holds great promise in
Ye Liu +10 more
wiley +1 more source
Proton pump inhibitor use and cardiovascular risk, all-cause, and cardiovascular mortality across baseline eGFR categories: a longitudinal study. [PDF]
Zhang T, Li T, Jin P.
europepmc +1 more source
Ubiquitination‐Driven Reprogramming of Proteostasis in Metastasis
The DCAF12–TRiC/CCT axis is a key regulator of metastasis in cancer. By reprogramming proteostasis to ensure efficient protein folding, it drives progression through a dual mechanism: enhancing cancer cell motility and invasiveness while concurrently activating pro‐growth and survival pathways.
Dongping Wei, Jiayan Chen, Yaping Xu
wiley +1 more source

