Results 151 to 160 of about 143,596 (340)

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

Activity of Fluoroquinolones and Proton Pump Inhibitors against Resistant Oral Bacterial Biofilms, in silico and in vitro Analysis

Polish Journal of Microbiology
Oral bacterial infections are a great health concern worldwide especially in diabetic patients. Emergence of antimicrobial resistance with reference to biofilms in oral cavity is of great concern.
Kamran Muhammad, Raza Muhammad, Ullah Riaz, Alotaibi Amal, Bano Ràheela, Zaman Ali, Chaman Sadia, Iqbal Kashif, Rasool Shahid, Amin Adnan   +9 more
doaj   +1 more source

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

Advanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards, Ella‐May Hards, Sofia N. dos Santos, Hannah E. Greenwood, Madeleine E. George, Andrea Emanuelli, Muhammet Tanc, Thomas R. Eykyn, Timothy H. Witney   +8 more
wiley   +1 more source

Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study

Gut, 2017
K. Cheung, E. Chan, A. Wong, Lijia Chen, I. Wong, W. Leung   +5 more
semanticscholar   +1 more source

Gecko‐Inspired Adhesive for Robotic Grippers with Excellent Ultra‐Low‐Temperature Adhesion Performance

Advanced Science, EarlyView.
Phenyl and vinyl groups are used to modify conventional polydimethylsiloxane (PDMS) to yield poly(methylphenylvinylsiloxane) (PMPVS). PMPVS‐based gecko‐inspired arrays with mushroom tips exhibit superior adhesion strength of 36.7 kPa even at −80 °C, which enhances by 5143% compared to PDMS‐based arrays (0.7 kPa at −70 °C).
Jiabao Feng, Hong Zhu, Yadong Lv, Qi Yang, Guangxian Li, Miqiu Kong, Wei Pu   +6 more
wiley   +1 more source

AB0469 PROTON PUMP INHIBITORS MAY IMPAIR RESPONSE TO TNF-INHIBITORS IN SPONDYLOARTHRITIS PATIENTS [PDF]

, 2021
M Masson, Marie Kostine, Thomas Barnetche, Alain Saraux, Adeline Ruyssen‐Witrand, Thierry Thomas, Daniel Wendling, Marie‐Elise Truchetet, Christophe Richez, Thierry Schaeverbeke   +9 more
openalex   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

The frequency of CYP2C19 genetic polymorphisms in Russian patients with peptic ulcers treated with proton pump inhibitors

Pharmacogenomics and Personalized Medicine, 2015
DA Sychev,1,2 NP Denisenko,1,2 ZM Sizova,2 AV Grachev,3 KA Velikolug4 1Russian Medical Academy of Post-Graduate Education, 2I.M. Sechenov First Moscow State Medical University, 3SM-Clinic, 4Out-patient department Number 51 branch 3, Moscow, Russia ...
Sychev DA, Denisenko NP, Sizova ZM, Grachev AV, Velikolug KA   +4 more
doaj  

Over prescription of Proton Pump Inhibitors on discharge of Medical Inpatients

, 2017
Sarmistha Biswas, ABM Abu Sufian, Prodip Kumar Sarkar, Mostofa Kamal Chowdhury, Joybaer Anam Chowdhury, Chandra Bala, Md. Rafiqul Islam, HAM Nazmul Ahasan, MA Kashem   +8 more
openalex   +2 more sources

Five‐day proton pump inhibitor‐based quadruple therapy regimen is more effective than 7‐day triple therapy regimen for Helicobacter pylori infection [PDF]

, 2001
Akihito Nagahara, Hiroto Miwa, Tetsuya Yamada, Akihiko Kurosawa, Ryuichi Ohkura, Nobuhiro Sato   +5 more
openalex   +1 more source