Results 261 to 270 of about 125,484 (349)
Metal halide perovskite quantum dots (PQDs) have been extensively explored due to their unique optical/optoelectronic properties such as tunable wavelength, narrow emission, and high photoluminescence quantum efficiency. This critical review article is an overview of the fabrication methods, degradation mechanisms of PQDs and explores strategies for ...
Sikandar Aftab+6 more
wiley +1 more source
ROR1 represents a promising target for the development of novel antiproliferative compounds, giving its high expression in different cancer cell lines. The present study describes the workflow leading to the design, synthesis, and characterization of a series of para‐phenylenediamine‐based compounds able to interact with the target kinase, inhibiting ...
Gerardina Smaldone+17 more
wiley +1 more source
Intravenous proton pump inhibitors <i>vs</i> oral potassium competitive acid blockers before endoscopic treatment of bleeding peptic ulcers. [PDF]
Lim NR, Chung WC.
europepmc +1 more source
Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer‐Related Pathways
Continuing our research aimed at discovering new BAG3 modulators as attractive anticancer drug candidates, we performed a screening campaign on an in‐house library, including compounds featuring a large variety of scaffolds. The obtained results induced us to focus on the triazole moiety and, following a stepwise structural refinement of the scaffold ...
Dafne Ruggiero+10 more
wiley +1 more source
Pitstop 2 binds to the clathrin terminal domain. This work explores the nature of the benzylidene moiety, R. The synthesis of 56 novel analogues reveals enhanced potency of a multiple analogues, with catechol‐free 2,3‐dihydroxybenzo[b][1,4]dioxone (54) returning a 1.2 μm IC50, ca 10‐fold more active than Pitstop 2. Pitstop 2, (Z)‐N‐(5‐(4‐bromenzylidene)
Kate Prichard+10 more
wiley +1 more source
Association between the use of proton pump inhibitors and serum PSA levels in the general U.S. population. [PDF]
Bioletto F+9 more
europepmc +1 more source
Several derivatives incorporating five‐membered aromatic rings are described in this review as bile acid receptor modulators, particularly targeting the farnesoid X receptor and the G protein‐coupled bile acid receptor 1. This review provides a comprehensive analysis of patents and literature that is useful to support researchers in the design of new ...
Claudia Finamore+5 more
wiley +1 more source
Concomitant use of metformin and proton pump inhibitors increases vitamin B12 deficiency risk in type 2 diabetes. [PDF]
Jung C, Park S, Kim H.
europepmc +1 more source