Results 261 to 270 of about 125,484 (349)

Perovskite Quantum Dots: Fabrication, Degradation, and Enhanced Performance Across Solar Cells, Optoelectronics, and Quantum Technologies

open access: yesCarbon Energy, EarlyView.
Metal halide perovskite quantum dots (PQDs) have been extensively explored due to their unique optical/optoelectronic properties such as tunable wavelength, narrow emission, and high photoluminescence quantum efficiency. This critical review article is an overview of the fabrication methods, degradation mechanisms of PQDs and explores strategies for ...
Sikandar Aftab   +6 more
wiley   +1 more source

Novel Para‐Phenylenediamine‐Based Derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An In Vitro Preliminary Characterization

open access: yesChemMedChem, EarlyView.
ROR1 represents a promising target for the development of novel antiproliferative compounds, giving its high expression in different cancer cell lines. The present study describes the workflow leading to the design, synthesis, and characterization of a series of para‐phenylenediamine‐based compounds able to interact with the target kinase, inhibiting ...
Gerardina Smaldone   +17 more
wiley   +1 more source

Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer‐Related Pathways

open access: yesChemMedChem, Accepted Article.
Continuing our research aimed at discovering new BAG3 modulators as attractive anticancer drug candidates, we performed a screening campaign on an in‐house library, including compounds featuring a large variety of scaffolds. The obtained results induced us to focus on the triazole moiety and, following a stepwise structural refinement of the scaffold ...
Dafne Ruggiero   +10 more
wiley   +1 more source

Are Children with Cystic Fibrosis Who Are Treated With a Proton-Pump Inhibitor at Risk for Vitamin B 12 Deficiency?

open access: bronze, 2001
Henriëtte ter Heide   +6 more
openalex   +1 more source

Inhibition of the Clathrin Terminal Domain—Amphiphysin Protein–Protein Interaction. Probing the Pitstop 2 Aromatic Moiety

open access: yesChemMedChem, EarlyView.
Pitstop 2 binds to the clathrin terminal domain. This work explores the nature of the benzylidene moiety, R. The synthesis of 56 novel analogues reveals enhanced potency of a multiple analogues, with catechol‐free 2,3‐dihydroxybenzo[b][1,4]dioxone (54) returning a 1.2 μm IC50, ca 10‐fold more active than Pitstop 2. Pitstop 2, (Z)‐N‐(5‐(4‐bromenzylidene)
Kate Prichard   +10 more
wiley   +1 more source

Association between the use of proton pump inhibitors and serum PSA levels in the general U.S. population. [PDF]

open access: yesWorld J Urol
Bioletto F   +9 more
europepmc   +1 more source

The Role of Five‐Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview

open access: yesChemMedChem, EarlyView.
Several derivatives incorporating five‐membered aromatic rings are described in this review as bile acid receptor modulators, particularly targeting the farnesoid X receptor and the G protein‐coupled bile acid receptor 1. This review provides a comprehensive analysis of patents and literature that is useful to support researchers in the design of new ...
Claudia Finamore   +5 more
wiley   +1 more source

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