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Esomeprazole: a proton pump inhibitor

Expert Review of Gastroenterology & Hepatology, 2009
Proton pump inhibitors (PPIs) are the most potent inhibitors of gastric acid secretion available, and they are effective for treating all acid-related disorders. Esomeprazole is one of several most recent PPIs that became available to the market in 2001.
Vic Velanovich   +2 more
openaire   +3 more sources

Proton Pump Inhibitors

2017
Guidelines generally recommend proton pump inhibitors (PPIs) over histamine type 2 receptor antagonists when acid suppression is advocated because of a longer duration of action, a superior ability in reducing acid secretion, and the absence of tachyphylaxis with repeated dosing.
Licia Pensabene, Geoffrey P. Davidson
openaire   +2 more sources

Proton Pump Inhibitors for Dyspepsia

Digestive Diseases, 2008
Proton pump inhibitors are widely used in many upper gastrointestinal disorders. Dyspepsia is a common problem in primary care and endoscopy is neither feasible nor affordable in the majority of patients. <i>Helicobacter pylori</i> eradication has been shown to be effective, but with the declining prevalence of <i>H.
openaire   +3 more sources

Proton pump inhibitors

BMJ, 2023
Danny, Jenkins, Ines, Modolell
openaire   +2 more sources

Overuse of proton pump inhibitors

Journal of Clinical Pharmacy and Therapeutics, 2000
There have been concerns raised about the potential adverse effects of proton pump inhibitors, especially with long-term use. In particular, their potent action can suppress the features and delay the diagnosis of gastric cancer, while prolonged exposure may hasten the development of gastric carcinoids.To examine the use of proton pump inhibitors in ...
Mark Naunton   +3 more
openaire   +3 more sources

Anaphylactic Reactions to Proton-Pump Inhibitors

Annals of Pharmacotherapy, 2000
OBJECTIVE: To report two cases of anaphylactic reactions to proton-pump inhibitors (PPIs). CASE SUMMARIES: A 54-year-old woman who had taken omeprazole in the past was treated with omeprazole 40 mg and developed periorbital edema, edema of the skin, pruritus, nausea, and vomiting about 45 minutes after taking one capsule.
Natsch, S.S.   +4 more
openaire   +4 more sources

Proton Pump Inhibitors

1999
The discovery and development of the proton pump inhibitor.- The discovery and development of the proton pump inhibitor.- Mechanism of action.- The gastric H, K ATPase.- Inhibition of the gastric proton pump.- The Pharmacology of proton pump inhibitors.- Inhibition of gastric acid secretion.- Consequences of gastric acid inihibition in animals ...
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The appropriate use of proton-pump inhibitors

Minerva Medica, 2018
The introduction of proton-pump inhibitors (PPIs) into clinical practice since about thirty years has greatly improved our therapeutic approach to acid-related diseases for their well recognized efficacy and safety. Accordingly, the role of surgery has been enormously reduced in this field.
Savarino, Vincenzo   +8 more
openaire   +3 more sources

Lansoprazole: A Proton Pump Inhibitor

Annals of Pharmacotherapy, 1996
OBJECTIVE: To summarize the published data on lansoprazole, a proton pump inhibitor approved by the Food and Drug Administration for use in the treatment of duodenal ulcer, erosive esophagitis, and pathologic hypersecretory conditions (e.g., Zollinger-Ellison syndrome).
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An Overview of Proton Pump Inhibitors

Gastroenterology Nursing, 2003
Proton pump inhibitors are the standard of treatment for acid-related disorders. These disorders include gastroesophageal reflux disease and its complications (i.e., erosive esophagitis and Barrett's esophagus), peptic ulcer disease, Zollinger-Ellison syndrome, and idiopathic hypersecretion.
openaire   +2 more sources

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