Results 1 to 10 of about 5,204,838 (351)

Respiratory-gated proton beam therapy for intrahepatic cholangiocarcinoma without fiducial markers [PDF]

Radiation Oncology
Background Intrahepatic cholangiocarcinoma (ICC) is a challenging primary liver cancer with a poor prognosis, especially in unresectable cases. Traditional palliative irradiation is limited in reducing liver doses.
Akihito Okubo, Sae Matsumoto, Hiroyasu Tamamura, Yoshitaka Sato, Satoko Asahi, Hitoshi Tatebe, Kazutaka Yamamoto, Keiichiro Matsushita, Makoto Sasaki, Yoshikazu Maeda, Yuji Tameshige, Hajime Sunagozaka, Hiroyuki Aoyagi, Satoshi Shibata, Shigeyuki Takamatsu, Satoshi Kobayashi   +15 more
doaj   +2 more sources

Comparative evaluation of static and dynamic 4D dose recalculations in pencil beam scanning proton therapy for oesophageal cancer [PDF]

Physics and Imaging in Radiation Oncology
Background and purpose: The robustness of pencil beam scanned (PBS) proton plans to respiratory motion is often assessed in clinical practice by static 4D dose recalculations on selected 4D computed tomography (4DCT) phases.
Linus A. Carizzoni, Alexey Cherchik, Xia Li, Antony Lomax, Ye Zhang   +4 more
doaj   +2 more sources

Proton Therapy

Hematology/Oncology Clinics of North America, 2019
Proton therapy is a form of external beam radiotherapy that has several advantages over conventional photon (x-ray) radiotherapy. Protons are useful in 2 scenarios that apply to a large proportion of cancer patients: lack of exit dose allows for delivery of a therapeutic radiation dose to tumors in challenging anatomic locations, and reduction in ...
Michael J, LaRiviere, Patricia Mae G, Santos, Christine E, Hill-Kayser, James M, Metz   +3 more
  +6 more sources

Investigating the potential of proton therapy for hypoxia-targeted dose escalation in non-small cell lung cancer

Radiation Oncology, 2021
Background Hypoxia is known to be prevalent in solid tumors such as non-small cell lung cancer (NSCLC) and reportedly correlates with poor prognostic clinical outcome.
Andreas Köthe, Nicola Bizzocchi, Sairos Safai, Antony John Lomax, Damien Charles Weber, Giovanni Fattori   +5 more
doaj   +1 more source

Hypofractionated proton beam radiotherapy in patients with unresectable liver tumors: multi-institutional prospective results from the Proton Collaborative Group

Radiation Oncology, 2020
Background Recent advances in radiotherapy techniques have allowed ablative doses to be safely delivered to inoperable liver tumors. In this setting, proton beam radiotherapy (PBT) provides the means to escalate radiation dose to the target volume while ...
Jacob S. Parzen, William Hartsell, John Chang, Smith Apisarnthanarax, Jason Molitoris, Michael Durci, Henry Tsai, James Urbanic, Jonathan Ashman, Carlos Vargas, Craig Stevens, Peyman Kabolizadeh   +11 more
doaj   +1 more source

Prognostic impact of the “Sekhar grading system for cranial Chordomas” in patients treated with pencil beam scanning proton therapy: an institutional analysis

Radiation Oncology, 2020
Background Skull base chordomas are rare and heterogeneously behaving tumors. Though still classified as benign they can grow rapidly, are locally aggressive, and have the potential to metastasize. To adapt the treatment to the specific needs of patients
Anna-Lena Hottinger, Beat Bojaxhiu, Frank Ahlhelm, Marc Walser, Barbara Bachtiary, Stefan Zepter, Tony Lomax, Alessia Pica, Damien C. Weber   +8 more
doaj   +1 more source

Feasibility of linac-based fractionated stereotactic radiotherapy and stereotactic radiosurgery for patients with up to ten brain metastases

Radiation Oncology, 2022
Background Linac-based fractionated stereotactic radiotherapy (fSRT) and stereotactic radiosurgery (SRS) are increasingly being used to manage patients with multiple metastases.
Masanori Hirata, Kazuaki Yasui, Naofumi Oota, Hirofumi Ogawa, Tsuyoshi Onoe, Sayo Maki, Yusuke Ito, Kenji Hayashi, Hirofumi Asakura, Shigeyuki Murayama, Koichi Mitsuya, Shoichi Deguchi, Katsumasa Nakamura, Nakamasa Hayashi, Tetsuo Nishimura, Hideyuki Harada   +15 more
doaj   +1 more source

Proton beam therapy [PDF]

British Journal of Cancer, 2005
Conventional radiation therapy directs photons (X-rays) and electrons at tumours with the intent of eradicating the neoplastic tissue while preserving adjacent normal tissue. Radiation-induced damage to healthy tissue and second malignancies are always a concern, however, when administering radiation.
Levin, W P, Kooy, H, Loeffler, J S, DeLaney, T F   +3 more
openaire   +2 more sources

Technical assessment of the NDI Polaris Vega optical tracking system

Radiation Oncology, 2021
The Polaris product line from Northern Digital Inc. is well known for accurate optical tracking measurements in research and medical environments. The Spectra position sensor, to date often found in image guided radiotherapy suites, has however reached ...
Giovanni Fattori, Antony John Lomax, Damien Charles Weber, Sairos Safai   +3 more
doaj   +1 more source

Commissioning and quality assurance of a novel solution for respiratory-gated PBS proton therapy based on optical tracking of surface markers

Zeitschrift für Medizinische Physik, 2022
We present the commissioning and quality assurance of our clinical protocol for respiratory gating in pencil beam scanning proton therapy for cancer patients with moving targets.
Giovanni Fattori, Jan Hrbacek, Harald Regele, Christian Bula, Alexandre Mayor, Stefan Danuser, David C. Oxley, Urs Rechsteiner, Martin Grossmann, Riccardo Via, Till T. Böhlen, Alessandra Bolsi, Marc Walser, Michele Togno, Emma Colvill, Daniel Lempen, Damien C. Weber, Antony J. Lomax, Sairos Safai   +18 more
doaj   +1 more source