Results 1 to 10 of about 260,677 (342)

Temporal dynamics of lymphocytes in prostate cancer patients treated with proton therapy [PDF]

Frontiers in Oncology
Radiotherapy can be both immunosuppressive and immunostimulatory. Radiation-induced lymphopenia (RIL) is an ongoing challenge in cancer treatment.
Sarah Salih Al-Hamami, Samuel Kurucz, Vladimír Vondráček, Vladimír Pekar, Michal Andrlík, Kateřina Dědečková, Iva Benešová, Alexandra Haas, Barbora Ondrová, Andrea Pasztorová, Pavel Vítek, Jiří Kubeš   +11 more
doaj   +2 more sources

Topogram and 3DCT geometry calibration for image-guided proton therapy with in-room CT-on-rails [PDF]

Physics and Imaging in Radiation Oncology
In-room computer tomography (CT) on-rails scanners are available in proton therapy centers but often limited to control imaging, due to geometric distortion and lack of integration.
Giovanni Fattori, Riccardo Via, Antony J. Lomax, Sairos Safai   +3 more
doaj   +2 more sources

Investigating the potential of proton therapy for hypoxia-targeted dose escalation in non-small cell lung cancer

Radiation Oncology, 2021
Background Hypoxia is known to be prevalent in solid tumors such as non-small cell lung cancer (NSCLC) and reportedly correlates with poor prognostic clinical outcome.
Andreas Köthe, Nicola Bizzocchi, Sairos Safai, Antony John Lomax, Damien Charles Weber, Giovanni Fattori   +5 more
doaj   +1 more source

Hypofractionated proton beam radiotherapy in patients with unresectable liver tumors: multi-institutional prospective results from the Proton Collaborative Group

Radiation Oncology, 2020
Background Recent advances in radiotherapy techniques have allowed ablative doses to be safely delivered to inoperable liver tumors. In this setting, proton beam radiotherapy (PBT) provides the means to escalate radiation dose to the target volume while ...
Jacob S. Parzen, William Hartsell, John Chang, Smith Apisarnthanarax, Jason Molitoris, Michael Durci, Henry Tsai, James Urbanic, Jonathan Ashman, Carlos Vargas, Craig Stevens, Peyman Kabolizadeh   +11 more
doaj   +1 more source

Prognostic impact of the “Sekhar grading system for cranial Chordomas” in patients treated with pencil beam scanning proton therapy: an institutional analysis

Radiation Oncology, 2020
Background Skull base chordomas are rare and heterogeneously behaving tumors. Though still classified as benign they can grow rapidly, are locally aggressive, and have the potential to metastasize. To adapt the treatment to the specific needs of patients
Anna-Lena Hottinger, Beat Bojaxhiu, Frank Ahlhelm, Marc Walser, Barbara Bachtiary, Stefan Zepter, Tony Lomax, Alessia Pica, Damien C. Weber   +8 more
doaj   +1 more source

Feasibility of linac-based fractionated stereotactic radiotherapy and stereotactic radiosurgery for patients with up to ten brain metastases

Radiation Oncology, 2022
Background Linac-based fractionated stereotactic radiotherapy (fSRT) and stereotactic radiosurgery (SRS) are increasingly being used to manage patients with multiple metastases.
Masanori Hirata, Kazuaki Yasui, Naofumi Oota, Hirofumi Ogawa, Tsuyoshi Onoe, Sayo Maki, Yusuke Ito, Kenji Hayashi, Hirofumi Asakura, Shigeyuki Murayama, Koichi Mitsuya, Shoichi Deguchi, Katsumasa Nakamura, Nakamasa Hayashi, Tetsuo Nishimura, Hideyuki Harada   +15 more
doaj   +1 more source

Sensitivity analysis of Monte Carlo model of a gantry-mounted passively scattered proton system [PDF]

, 2020
PURPOSE: This study aimed to present guidance on the correlation between treatment nozzle and proton source parameters, and dose distribution of a passive double scattering compact proton therapy unit, known as Mevion S250.
Baradaran-Ghahfarokhi, Milad, Prusator, Michael T, Reynoso, Francisco, Sun, Baozhou, Zhao, Tianyu   +4 more
core   +2 more sources

Technical assessment of the NDI Polaris Vega optical tracking system

Radiation Oncology, 2021
The Polaris product line from Northern Digital Inc. is well known for accurate optical tracking measurements in research and medical environments. The Spectra position sensor, to date often found in image guided radiotherapy suites, has however reached ...
Giovanni Fattori, Antony John Lomax, Damien Charles Weber, Sairos Safai   +3 more
doaj   +1 more source

Commissioning and quality assurance of a novel solution for respiratory-gated PBS proton therapy based on optical tracking of surface markers

Zeitschrift für Medizinische Physik, 2022
We present the commissioning and quality assurance of our clinical protocol for respiratory gating in pencil beam scanning proton therapy for cancer patients with moving targets.
Giovanni Fattori, Jan Hrbacek, Harald Regele, Christian Bula, Alexandre Mayor, Stefan Danuser, David C. Oxley, Urs Rechsteiner, Martin Grossmann, Riccardo Via, Till T. Böhlen, Alessandra Bolsi, Marc Walser, Michele Togno, Emma Colvill, Daniel Lempen, Damien C. Weber, Antony J. Lomax, Sairos Safai   +18 more
doaj   +1 more source

Deep learning method for prediction of patient-specific dose distribution in breast cancer

Radiation Oncology, 2021
Background Patient-specific dose prediction improves the efficiency and quality of radiation treatment planning and reduces the time required to find the optimal plan. In this study, a patient-specific dose prediction model was developed for a left-sided
Sang Hee Ahn, EunSook Kim, Chankyu Kim, Wonjoong Cheon, Myeongsoo Kim, Se Byeong Lee, Young Kyung Lim, Haksoo Kim, Dongho Shin, Dae Yong Kim, Jong Hwi Jeong   +10 more
doaj   +1 more source