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Physics in Medicine & Biology, 2021 Abstract Radiation therapy treatments are typically planned based on a single image set, assuming that the patient’s anatomy and its position relative to the delivery system remains constant during the course of treatment. Similarly, the prescription dose assumes constant biological dose-response over the treatment course.
Harald Paganetti +3 more
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The British Journal of Radiology, 2019 Proton beam therapy is a highly conformal form of radiation therapy, which currently represents an important therapeutic component in multidisciplinary management in paediatric oncology. The precise adjustability of protons results in a reduction of radiation-related long-term side-effects and secondary malignancy induction, which is of particular ...
Thomas, Heike, Timmermann, Beate
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British Journal of Cancer, 2005 Conventional radiation therapy directs photons (X-rays) and electrons at tumours with the intent of eradicating the neoplastic tissue while preserving adjacent normal tissue. Radiation-induced damage to healthy tissue and second malignancies are always a concern, however, when administering radiation.
William P. Levin +3 more
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Temporal dynamics of lymphocytes in prostate cancer patients treated with proton therapy [PDF]
Frontiers in OncologyRadiotherapy can be both immunosuppressive and immunostimulatory. Radiation-induced lymphopenia (RIL) is an ongoing challenge in cancer treatment.
Sarah Salih Al-Hamami +11 more
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Topogram and 3DCT geometry calibration for image-guided proton therapy with in-room CT-on-rails [PDF]
Physics and Imaging in Radiation OncologyIn-room computer tomography (CT) on-rails scanners are available in proton therapy centers but often limited to control imaging, due to geometric distortion and lack of integration.
Giovanni Fattori +3 more
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Image-Guided Proton Therapy: A Comprehensive Review
Cancers, 2023 Simple Summary In proton therapy, there is a sharp peak in the delivered dose followed by a rapid falloff, known as the Bragg peak, which is not present in photons.
Shelby A. Lane, J. Slater, Gary Y. Yang
semanticscholar +1 more source
A review of proton therapy – Current status and future directions
Precision Radiation Oncology, 2022 The original rationale for proton therapy was its highly conformal depth‐dose distributions compared to photons, which allow greater sparing of normal tissues and escalation of tumor doses, thus potentially improving outcomes.
R. Mohan
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Srpski arhiv za celokupno lekarstvo, 2021 Proton beam therapy (PBT) is an advanced type of radiotherapy that shows a dosimetric advantage over photon beam therapy and provides superior dose distribution. PBT may improve patient survival by improving the local disease control while reducing toxicity to normal organs, which may result in fewer treatment-related complications.
Marija Popovic-Vukovic +4 more
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Radiosensitization Effect of Gold Nanoparticles in Proton Therapy
Frontiers in Public Health, 2021 The number of proton therapy facilities and the clinical usage of high energy proton beams for cancer treatment has substantially increased over the last decade.
C. Cunningham +5 more
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National Protocol for Model-Based Selection for Proton Therapy in Head and Neck Cancer
International Journal of Particle Therapy, 2021 In the Netherlands, the model-based approach is used to identify patients with head and neck cancer who may benefit most from proton therapy in terms of prevention of late radiation-induced side effects in comparison with photon therapy. To this purpose,
J. Langendijk +13 more
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