Results 1 to 10 of about 5,021,050 (358)
Physics in Medicine & Biology, 2021 Abstract Radiation therapy treatments are typically planned based on a single image set, assuming that the patient’s anatomy and its position relative to the delivery system remains constant during the course of treatment. Similarly, the prescription dose assumes constant biological dose-response over the treatment course.
Harald Paganetti +3 more
openaire +4 more sources
The British Journal of Radiology, 2019 Proton beam therapy is a highly conformal form of radiation therapy, which currently represents an important therapeutic component in multidisciplinary management in paediatric oncology. The precise adjustability of protons results in a reduction of radiation-related long-term side-effects and secondary malignancy induction, which is of particular ...
Thomas, Heike, Timmermann, Beate
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On the accuracy of Monte Carlo based beam dynamics models for the degrader in proton therapy facilities [PDF]
, 2017 In a cyclotron-based proton therapy facility, the energy changes are performed by means of a degrader of variable thickness. The interaction of the proton beam with the degrader creates energy tails and increases the beam emittance. A precise model of the degraded beam properties is important not only to better understand the performance of a facility ...
Adelmann, A. +5 more
arxiv +3 more sources
The physics of proton therapy [PDF]
Physics in Medicine and Biology, 2015 The physics of proton therapy has advanced considerably since it was proposed in 1946. Today analytical equations and numerical simulation methods are available to predict and characterize many aspects of proton therapy.
Newhauser, Wayne D., Zhang, Rui
core +5 more sources
British Journal of Cancer, 2005 Conventional radiation therapy directs photons (X-rays) and electrons at tumours with the intent of eradicating the neoplastic tissue while preserving adjacent normal tissue. Radiation-induced damage to healthy tissue and second malignancies are always a concern, however, when administering radiation.
William P. Levin +3 more
openalex +3 more sources
European Oncology & Haematology, 2018 Ob kirurškem in sistemskem zdravljenju je radioterapija eden od treh stebrov zdravljenja raka. Izjemen tehnološki razvoj na področju pospeševalnikov nabitih delcev je pripeljal do uveljavitve protonske radioterapije kot terapije izbora pri določenih ...
Casar, Božidar, Strojan, Primož
core +5 more sources
Image-Guided Proton Therapy: A Comprehensive Review
Cancers, 2023 Simple Summary In proton therapy, there is a sharp peak in the delivered dose followed by a rapid falloff, known as the Bragg peak, which is not present in photons.
Shelby A. Lane, J. Slater, Gary Y. Yang
semanticscholar +1 more source
A review of proton therapy – Current status and future directions
Precision Radiation Oncology, 2022 The original rationale for proton therapy was its highly conformal depth‐dose distributions compared to photons, which allow greater sparing of normal tissues and escalation of tumor doses, thus potentially improving outcomes.
R. Mohan
semanticscholar +1 more source
Srpski arhiv za celokupno lekarstvo, 2021 Proton beam therapy (PBT) is an advanced type of radiotherapy that shows a dosimetric advantage over photon beam therapy and provides superior dose distribution. PBT may improve patient survival by improving the local disease control while reducing toxicity to normal organs, which may result in fewer treatment-related complications.
Marija Popovic-Vukovic +4 more
openaire +4 more sources
Radiosensitization Effect of Gold Nanoparticles in Proton Therapy
Frontiers in Public Health, 2021 The number of proton therapy facilities and the clinical usage of high energy proton beams for cancer treatment has substantially increased over the last decade.
C. Cunningham +5 more
semanticscholar +1 more source