Results 11 to 20 of about 5,053,091 (357)

Investigating the potential of proton therapy for hypoxia-targeted dose escalation in non-small cell lung cancer

open access: yesRadiation Oncology, 2021
Background Hypoxia is known to be prevalent in solid tumors such as non-small cell lung cancer (NSCLC) and reportedly correlates with poor prognostic clinical outcome.
Andreas Köthe   +5 more
doaj   +1 more source

A Critical Review of LET-Based Intensity-Modulated Proton Therapy Plan Evaluation and Optimization for Head and Neck Cancer Management

open access: yesInternational Journal of Particle Therapy, 2021
In this review article, we review the 3 important aspects of linear-energy-transfer (LET) in intensity-modulated proton therapy (IMPT) for head and neck (H&N) cancer management.
W. Deng   +8 more
semanticscholar   +1 more source

Hypofractionated proton beam radiotherapy in patients with unresectable liver tumors: multi-institutional prospective results from the Proton Collaborative Group

open access: yesRadiation Oncology, 2020
Background Recent advances in radiotherapy techniques have allowed ablative doses to be safely delivered to inoperable liver tumors. In this setting, proton beam radiotherapy (PBT) provides the means to escalate radiation dose to the target volume while ...
Jacob S. Parzen   +11 more
doaj   +1 more source

Prognostic impact of the “Sekhar grading system for cranial Chordomas” in patients treated with pencil beam scanning proton therapy: an institutional analysis

open access: yesRadiation Oncology, 2020
Background Skull base chordomas are rare and heterogeneously behaving tumors. Though still classified as benign they can grow rapidly, are locally aggressive, and have the potential to metastasize. To adapt the treatment to the specific needs of patients
Anna-Lena Hottinger   +8 more
doaj   +1 more source

Feasibility of linac-based fractionated stereotactic radiotherapy and stereotactic radiosurgery for patients with up to ten brain metastases

open access: yesRadiation Oncology, 2022
Background Linac-based fractionated stereotactic radiotherapy (fSRT) and stereotactic radiosurgery (SRS) are increasingly being used to manage patients with multiple metastases.
Masanori Hirata   +15 more
doaj   +1 more source

MR-guided proton therapy: a review and a preview

open access: yesRadiation Oncology, 2020
Background The targeting accuracy of proton therapy (PT) for moving soft-tissue tumours is expected to greatly improve by real-time magnetic resonance imaging (MRI) guidance.
A. Hoffmann   +12 more
semanticscholar   +1 more source

CT-on-Rails Versus In-Room CBCT for Online Daily Adaptive Proton Therapy of Head-and-Neck Cancers

open access: yesCancers, 2021
Simple Summary Daily adaptive proton therapy will allow the unique properties of protons to be fully exploited. Cone-beam CT (CBCT) is the primary imaging modality considered for daily adaptation due to its low cost, compactness, and thus wide ...
K. Nesteruk   +5 more
semanticscholar   +1 more source

Deep learning method for prediction of patient-specific dose distribution in breast cancer

open access: yesRadiation Oncology, 2021
Background Patient-specific dose prediction improves the efficiency and quality of radiation treatment planning and reduces the time required to find the optimal plan. In this study, a patient-specific dose prediction model was developed for a left-sided
Sang Hee Ahn   +10 more
doaj   +1 more source

Commissioning and quality assurance of a novel solution for respiratory-gated PBS proton therapy based on optical tracking of surface markers

open access: yesZeitschrift für Medizinische Physik, 2022
We present the commissioning and quality assurance of our clinical protocol for respiratory gating in pencil beam scanning proton therapy for cancer patients with moving targets.
Giovanni Fattori   +18 more
doaj   +1 more source

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