Noisy probing dose facilitated dose prediction for pencil beam scanning proton therapy: Physics enhances generalizability. [PDF]
Zhang L +15 more
europepmc +1 more source
Multiscale perspectives on how excess charges in soft lead halide perovskites induce operational instability in photovoltaic devices are presented. Localized carriers formed under thermodynamic non‐equilibrium states modify atomistic interactions and drive lattice distortions, accelerating device degradation.
Joo‐Hong Lee +6 more
wiley +1 more source
ABSTRACT Aim Carbon‐ion radiotherapy (CIRT) provides superior dose distribution and higher biological effectiveness than conventional X‐ray radiotherapy and has emerged as a promising component of multidisciplinary treatment for advanced pancreatic ductal adenocarcinoma (PDAC).
Kenichiro Araki +9 more
wiley +1 more source
Biologically Effective Dose-Optimized Multi-Intensity-Modulated Proton Therapy: A Biologically Comparable Alternative to Proton Arc Therapy. [PDF]
Shinde N +9 more
europepmc +1 more source
Natural Aging of Biomaterials in Ambient and Physiological Environments
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley +1 more source
Commissioning of LUNA three-dimensional surface-guided radiotherapy in full rotating gantry proton therapy system. [PDF]
Lew KS +11 more
europepmc +1 more source
Structural and Functional Siderophore Remodeling by Enzymatic Delipidation
A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog +5 more
wiley +1 more source
Potential normal tissue sparing in vulvar cancer using intensity modulated proton therapy versus volumetric modulated arc therapy. [PDF]
Prins AC +5 more
europepmc +1 more source
Generalizable Strategies for the Synthesis of Cereblon‐Recruiting PROTAC Prodrugs
Cereblon‐recruiting PROTACs remain challenging to derivatize for prodrug‐based delivery. In this study, three complementary conjugation strategies enabled the efficient synthesis of cleavable PROTAC prodrugs with tunable release kinetics that can be incorporated into a library of PEGylated constructs and bottlebrush prodrugs.
Aiden X. Wang +7 more
wiley +1 more source
Dynamic range optimization for treatment time reduction in respiratory-gated proton therapy using RayStation v2025. [PDF]
Cho S, Yu JI, Park HC, Jo K.
europepmc +1 more source

