Results 171 to 180 of about 271,177 (332)

Spot-Scanning Proton Therapy Patient-Specific Quality Assurance: Results from 309 Treatment Plans [PDF]

, 2014
Dennis Mackin, X Zhu, Falk Poenisch, Heng Li, Narayan Sahoo, M. Kerr, Charles Holmes, Yupeng Li, MingFwu Lii, Richard Wu, Kazumichi Suzuki, Michael T. Gillin, Steven J. Frank, David R. Grosshans, Xiaodong Zhang   +14 more
openalex   +1 more source

First Generation Proteolysis Targeting Chimeras (PROTACs) for the Treatment of Progeria

Advanced Science, EarlyView.
We report the first PROTACs designed to degrade progerin, introducing a novel therapeutic approach for progeria. The best compound, UCM‐18142, significantly reduces progerin levels and improves key disease phenotypes in patient‐derived cells and in the LmnaG609G/G609G mouse model, paving the way for new treatment strategies targeting the root cause of ...
Jon Macicior‐Michelena, Marcelino Telechea, Daniel Fernández, Alba García‐Martín, Ángeles Canales, Silvia Ortega‐Gutiérrez   +5 more
wiley   +1 more source

Long Term Results of Proton Therapy in Adult Infradiaphragmatic Lymphoma. [PDF]

Int J Part Ther
Jiang C, Hoover T, Baron J, Han X, Li B, Gao Y, Kim M, Hubbeling H, Chong EA, Carter J, Svoboda J, Schuster SJ, Landsburg DJ, Nasta SD, Plastaras J, LaRiviere M.   +15 more
europepmc   +1 more source

Error identification and compensation in large manipulators with application in cancer proton therapy [PDF]

, 2004
Marco Antônio Meggiolaro, Steven Dubowsky, Constantinos Mavroidis   +2 more
openalex   +1 more source

Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao, Jianjun Zou, Chen Zhou, Yingui Wang, Yiman Liu, Yanqing Zhou, Yuxiang Wang, Xinyu Zhang, Huishu Yang, Hongjie Yin, Dongsheng Bai, Yue Zhao, Na Lu   +12 more
wiley   +1 more source

Fluorescent nuclear track detectors for out-of-field neutron dosimetry in proton therapy. [PDF]

Med Phys
Schmidt S, Muñoz ID, Yukihara EG, Vedelago J.   +3 more
europepmc   +1 more source

Fiducial Markers, Saline, and Balloons to Locate and Stabilize the Prostate during Proton Therapy

, 2015
R. A. Zeitlin, M. McPhillips, Stephanie E. Harris, Stephen E. Mandia, Christopher Williams, Joseph Costa, Christopher G. Morris, Zhong Su, Zuofeng Li, Nancy P. Mendenhall   +9 more
openalex   +1 more source

Power Calculation And Design Considerations For Randomized Controlled Trials Testing Toxicity Reduction With Proton Therapy In Head And Neck Cancer [PDF]

, 2020
A. van der Schaaf, Christian Rønn Hansen, L. Van den Bosch, Hans Paul van der Laan, R. Steenbakkers, E. Shuit, Stefan Both, Johannes A. Langendijk   +7 more
openalex   +1 more source

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +12 more
wiley   +1 more source

Feasibility of reduced setup uncertainty in intensity-modulated proton therapy for mediastinal lymphoma. [PDF]

Phys Imaging Radiat Oncol
Pisciotta P, Hengeveld A, Korevaar EW, Visser S, Wagenaar D, Klinker P, Maduro JH, Langendijk JA, Niezink AG, Both S.   +9 more
europepmc   +1 more source