Results 161 to 170 of about 147,513 (305)

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Technical Considerations on Proton Therapy in NRG's Multi-Institutional Clinical Trials. [PDF]

Int J Radiat Oncol Biol Phys
Liang X, Taylor PA, Li H, Paganetti H, Pankuch M, Beltan CJ, Flampouri S, Hoppe BS, Kooy H, Lin H, Lin L, Liu W, Sahoo N, Simone CB, Teo BK, Xiao Y, Zhou J, Buchsbaum JC.   +17 more
europepmc   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

Proton Therapy

Proton therapy is rapidly expanding in patient care throughout the world. Once limited to a few centers of care, continued process improvements in the scope and design of proton facilities have now permitted proton centers to develop at an enterprise ...

core   +1 more source

Modern proton therapy in prostate cancer: precision in practice. [PDF]

Front Oncol
Yacoub I, Khalil J, Wei S, Hsieh K, Chhabra AM, Mehta KJ, Oska C, Zhu L, Choi JI, Simone CB.   +9 more
europepmc   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

Advanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi, Jingrui Cao, Tong Wu, Guang Yang, YaWen Yang, Shixin Zhang, Wenwen Su, Hongyu Chu, Yangyang Zhao, Shan Jiang, Qiong Wu, Dongxu Jiao, Fangfang Chen   +12 more
wiley   +1 more source

Determination of HU override for gold fiducial markers in proton therapy. [PDF]

J Appl Clin Med Phys
Zhang X, Andriotty M, Yue NJ, Nie K, Zhang Y, Davis R, Parikh R, Xiong Z, Ma C, Wang X.   +9 more
europepmc   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Design and Deployment of a Proton Therapy Cone-Beam CT

, 2012
Objective : Cone-Beam CT (CBCT) has been successfully used for image-guided radiation therapy for about 10 years. The use of proton instead of photon beams for radiation therapy enables an optimal distribution of the prescribed dose delivered to the ...
Wikler, David, Maughan, Richard, Teo, Kevin, Annual Meeting of Proton Therapy Co-operative Group, Labarbe, Rudi, Lee, John Aldo, Rosa Seabra, José Carlos, Brousmiche, Sébastien   +7 more
core  

Artificial Intelligence in Proton Therapy: What Works, What Does Not, and What Is Next. [PDF]

Cancer J
Li H, Yang M, Ndassi DK, Meng S, Jia X.
europepmc   +1 more source