Results 51 to 60 of about 13,239 (184)
Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes
The FEBS Journal, EarlyView.During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb +4 more
wiley +1 more source
Bacterial Porphyrin Extraction and Quantification by LC/MS/MS Analysis
Bio-Protocol, 2015 Heme is an iron-containing porphyrin which acts as a prosthetic group in several enzymes involved in disparate functions, such as respiration and H2O2-scavenging.
Stefano Mancini, James Imlay
doaj +1 more source
Cutaneous Respirometry as Novel Technique to Monitor Mitochondrial Function: A Feasibility Study in Healthy Volunteers. [PDF]
PLoS ONE, 2016 The protoporphyrin IX-triplet state lifetime technique (PpIX-TSLT) is proposed as a potential clinical non-invasive tool to monitor mitochondrial function. This technique has been evaluated in several animal studies.
Floor Anneleen Harms +2 more
doaj +1 more source
GmDOF3.1‐GmCPX Module Regulates Nodulation and Nitrogen Fixation Abilities in Soybean
Plant Biotechnology Journal, EarlyView.ABSTRACT Soybean nodule nitrogen fixation is very important, which can provide a large amount of nitrogen supply for its own growth and that of other crops, but the mechanism is largely unclear. In the present study, a coproporphyrinogen oxidase gene, GmCPX, was identified to facilitate soybean nodulation and nitrogen‐fixation under the regulation of ...
Xinzhu Xing +10 more
wiley +1 more source
Brain Sciences, 2018 The CAALA (Complex Augmentation of ALA) regimen was developed with the goal of redressing some of the weaknesses of 5-aminolevulinic acid (5-ALA) use in glioblastoma treatment as it now stands.
Richard E. Kast +8 more
doaj +1 more source
Photochemistry and Photobiology, EarlyView.Photoproducts of the photosensitizer protoporphyrin IX (PpIX) may have diagnostic and therapeutic relevance in photodynamic diagnosis (PDD) and photodynamic therapy (PDT). These photoproducts possess fluorescence and photosensitizing properties and could serve as a complementary dosimetry index alongside photosensitizer photobleaching. The formation of
Sochi J. Ogbonna +2 more
wiley +1 more source
PLoS ONE, 2022 Combination of photosensitizers (PS) with nanotechnology can improve the therapeutic efficiency of clinical Photodynamic Therapy (PDT) by converting visible light reactive PSs into Near-Infrared (NIR) light responsive molecules using Harmonic ...
Ayan Barbora +6 more
doaj +1 more source
The effect of photodynamic therapy in head and neck cancer: A comprehensive review of in vivo models
Photochemistry and Photobiology, EarlyView.This review evaluates Photodynamic Therapy (PDT) in in vivo head and neck cancer models. PDT effectively generates ROS, reducing tumor growth, cell proliferation and angiogenesis while enhancing survival and immune responses. However, methodological heterogeneity highlights the urgent need for standardized dosimetric protocols to ensure reproducibility
Bibiana Padilha de Menezes da Silva +5 more
wiley +1 more source
Food Science and Technology Research, 2007 The formation of zinc protoporphyrin IX (ZnPP) and protoporphyrin IX (PP) in porcine heart mitochondria was investigated by fluorescent spectral analysis. The time-course study at 37°C and pH 5.5 with 100μM ZnCl2 showed a linear formation of ZnPP from oxymyoglobin after a lag-period (9h) at the formation rate of 0.46nmol/h. The formed amount of ZnPP is
ISHIKAWA, Hiroya +5 more
openaire +2 more sources
A low‐cost handheld device for monitoring cutaneous photosensitivity
Photochemistry and Photobiology, EarlyView.The cutaneous photosensitivity detection (CPD) device is a handheld contact‐based measurement device using 405 nm excitation and red fluorescence detection for monitoring skin phototoxicity risk after photodynamic therapy (PDT) procedures involving systemic aminolaevulinic acid (ALA) induced protoporphyrin IX (PpIX) photosensitization.
Md Asaduzzaman Rasel +4 more
wiley +1 more source